Though less discussed in the literature, slave patrols played a significant role in continuing and sustaining the system of slavery. While few scholars have dedicated attention to exploring the history of slave patrols in the United States (US), there remains a dearth of research analyzing the slave patrol system in Brazil, despite the existence of slavery in this area of the African Diaspora. Using a historical perspective, this article compares and examines the establishment, function, expansion of slave patrols in the US and Brazil between the 18th and 19th centuries. This article adds to the scholarly discourse and historical literature on the experiences and conditions of enslaved people in the African diaspora (i.e., US and Brazil) under the brutal watch of slave patrols. Future research and investigation is needed to gain nuanced understanding of slave patrols not only in these two specific geographical regions, but globally across the African diaspora.