This article takes as its starting point a 1961 conversation between James Baldwin and Lorraine Hansberry, where the latter first posed the question that would recur in Baldwin’s writings in the following years: “Is it necessary to integrate oneself into a burning house?” Although the phrase is often associated with Baldwin, who mostly used it as a metaphor for the racist nation, most famously in The Fire Next Time (1963), this article shows how Hansberry’s analysis of many African Americans’ skepticism toward integration into a “burning house” was situated in a global context of anticolonial, anti-capitalist, and feminist struggle. Writing within networks of Black internationalist feminists and presenting a multivalent and relational account of home, Hansberry revealed household labor and relations of intimacy to be central to the making and maintenance of empire, racism, and capitalism, as well as their contestation through acts and affects of insurgency.