Abstract:Conditions associated with impairments in insulin sensitivity (SI), such as obesity and type-II diabetes (T2D), often present with elevated NEFA. While lipid infusion studies have shown that increasing NEFA can impair glucose metabolism (1) , there are relatively few studies investigating the effect of NEFA elevation following fat loads of differing composition.Sixty healthy volunteers participated in a single-blind crossover trial. Subjects were randomly assigned to either 0.75 g/kg bodyweight (bw) of palm st… Show more
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