Insulin pen injection technique survey in patients with type 2 diabetes in mainland China in 2010

Ji, Jiajia; Lou, Qingqing

doi:10.1185/03007995.2014.895711

Cited by 51 publications

(61 citation statements)

References 19 publications

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“…Poor injection technique could also be an important reason for poor blood glucose control. Recently, a survey in mainland China showed that the insulin injection technique was often poor, and the rates of lipohypertrophy, bleeding and needle reuse were high . Our findings suggest that education on proper insulin injection technique should be emphasized.…”

Section: Discussionmentioning

confidence: 72%

Management status and its predictive factors in patients with type 2 diabetes in China: A Nationwide Multicenter Study

Lin

Lou

et al. 2015

Diabetes Metabolism Res

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Section: Discussionmentioning

confidence: 72%

Management status and its predictive factors in patients with type 2 diabetes in China: A Nationwide Multicenter Study

Lin

Lou

et al. 2015

Diabetes Metabolism Res

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“…Interrater reliability of reviewers regarding study relevancy was high (Kappa = 0.86). Nine studies took place in Asia, 14 in Europe, and one each in North America, Africa and a mix of different countries. The median of the mean ages was 46 years (range 6.5–63.8 years), and the median percentage of males represented in the sample was 50% (range 27.3–59.1%).…”

Section: Resultsmentioning

confidence: 99%

“…In addition, the median number of participants per study was 228 (range 54–4352), the median of mean disease duration was 10.0 years (range 2.8–17.0 years) and the median of mean insulin treatment duration was 9.3 years (range 3.0–15.0 years). When evaluated by the modified Newcastle–Ottawa quality assessment criteria, out of 5 possible points, one study received 5 points, seven studies received 4 points, 14 received 3 points, three received 2 points and one received 1 point.…”

Section: Resultsmentioning

confidence: 99%

Prevalence of lipohypertrophy in insulin‐treated diabetes patients: A systematic review and meta‐analysis

Deng

Zhang

Zhao

et al. 2017

J of Diabetes Invest

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Aims/IntroductionInsulin‐treated diabetes patients are at high risk for lipohypertrophy (LH), but this clinical problem has been overlooked by some medical professionals. In addition, studies differed from each other significantly in regard to the prevalence of LH. The present systematic review aimed to determine pooled prevalence levels of LH among insulin‐injecting diabetes patients.Materials and MethodsFour electronic databases (PubMed, EMBASE, The Cochrane Library and Scopus) were searched for eligible studies from their inception until April 2017, and reference lists were searched manually to identify additional studies. Studies containing data on LH in patients with diabetes mellitus were included. Meta‐analysis was carried out with a random effects model.ResultsA total of 26 studies with a total of 12,493 participants met the inclusion criteria. Meta‐analysis showed that the pooled prevalence of LH was 38% (95% confidence interval [CI] 29–46%, I 2 = 99.1%). The main influence on LH was the type of diabetes mellitus. The pooled prevalence of LH among patients with type 2 diabetes mellitus was higher than patients with type 1 diabetes mellitus (49%, 95% CI 23–74% vs 34%, 95% CI 19–49%). The pooled prevalence of LH of studies involving a mixed type of diabetes mellitus was 37% (95% CI 25–48%, I 2 = 98.3%).ConclusionThe prevalence of LH was high in insulin‐treated diabetes patients. It showed that diabetes nurses should screen for LH regularly in their patients, and teach them how to prevent LH in their daily management of diabetes mellitus.

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“…A cross-sectional survey regarding use of the insulin pens also revealed that 35.26% of type 2 diabetic patients had lipohypertrophy and 58.68% of the patients had symptoms of bleeding and bruising at the injection site, [18] suggesting that the insulin pens used for glycemic control may cause undesirable effects in some of the patients. In addition, the needle-free, easy-to-use jet injectors indeed showed high merits in avoiding the reuse of injection needles and simplifying procedures of insulin delivery.…”

Section: Discussionmentioning

confidence: 99%

Comparison of jet injector and insulin pen in controlling plasma glucose and insulin concentrations in type 2 diabetic patients

et al. 2017

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This study is conducted to investigate efficacy of an insulin jet injector and an insulin pen in treatment of type 2 diabetic patients. Sixty patients with type 2 diabetes were treated with rapid-acting insulin (regular insulin) and insulin analog (insulin aspart) using the jet injector and the pen in 4 successive test cycles. Postprandial glucose and insulin concentrations in blood were measured over time. Areas under curves of glucose and the insulin were calculated, and efficacy of 2 injection methods in treatment of the diabetes was compared. Regular insulin and insulin aspart administration by the jet injector showed significant decreases in plasma glucose levels as compared to the pen injection (P < 0.05). Postprandial plasma glucose excursions at the time points of 0.5 to 3 hours were obviously lower in the jet-treated patients than the pen-treated ones (P < 0.05). Postprandial plasma insulin levels were markedly higher in the jet-treated patients than the pen-treated ones (P < 0.05). Area under the glucose curve in the pen-treated patients was significantly increased as compared to the jet-treated ones (P < 0.01). Efficacy of the insulin jet injector in treatment of type 2 diabetic patients is obviously superior to the insulin pen in regulating plasma glucose and insulin levels.

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Insulin pen injection technique survey in patients with type 2 diabetes in mainland China in 2010

Cited by 51 publications

References 19 publications

Management status and its predictive factors in patients with type 2 diabetes in China: A Nationwide Multicenter Study

Management status and its predictive factors in patients with type 2 diabetes in China: A Nationwide Multicenter Study

Prevalence of lipohypertrophy in insulin‐treated diabetes patients: A systematic review and meta‐analysis

Comparison of jet injector and insulin pen in controlling plasma glucose and insulin concentrations in type 2 diabetic patients

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