Insulin and the kidneys: a contemporary view on the molecular basis
Rodrigo Daza-Arnedo,
Jorge Rico-Fontalvo,
Gustavo Aroca-Martínez
et al.
Abstract:Insulin is a hormone that is composed of 51 amino acids and structurally organized as a hexamer comprising three heterodimers. Insulin is the central hormone involved in the control of glucose and lipid metabolism, aiding in processes such as body homeostasis and cell growth. Insulin is synthesized as a large preprohormone and has a leader sequence or signal peptide that appears to be responsible for transport to the endoplasmic reticulum membranes. The interaction of insulin with the kidneys is a dynamic and … Show more
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