Insuffisances ovariennes prématurées

Bricaire, Léopoldine; Laroche, Emmanuelle; Bourcigaux, Nathalie; Donadille, Bruno; Christin-Maître, Sophie

doi:10.1016/j.lpm.2013.04.018

Cited by 13 publications

(2 citation statements)

References 25 publications

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“…According to the new guidelines of the European Society of Human Reproduction and Embryology, POI is defined as the loss of ovarian activity in a woman before the age of 40 with elevated gonadotrophin and decreased estrogen [3, 33, 34]. The diagnosis of POI requires simultaneous abnormal menstruation and biochemical abnormalities: oligomenorrhea/amenorrhea for at least 4 months and an elevated FSH level > 25 IU/L on two occasions (4 weeks apart) [35]. The patients include women younger than 40 years (which includes Turner Syndrome patients) and women older than 40 years, but older patients must be affected before the age of 40 [1, 36].…”

Section: Inflammatory Aging and Premature Ovarian Insufficiency (Poi)mentioning

confidence: 99%

Inflamm-Aging: A New Mechanism Affecting Premature Ovarian Insufficiency

Huang

et al. 2019

Journal of Immunology Research

132

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The normal function of ovaries, along with the secretion of sex hormones, is among the most important endocrine factors that maintain the female sexual characteristics and promote follicular development and ovulation. Premature ovarian insufficiency (POI) is a common cause in the etiology of female infertility. It is defined as the loss of ovarian function before the age of 40. The characteristics of POI are menstrual disorders, including amenorrhea and delayed menstruation, accompanied by a raised gonadotrophin level and decreased estradiol level. Inflammatory aging is a new concept in the research field of aging. It refers to a chronic and low-degree proinflammatory state which occurs with increasing age. Inflammatory aging is closely associated with multiple diseases, as excessive inflammation can induce the inflammatory lesions in certain organs of the body. In recent years, studies have shown that inflammatory aging plays a significant role in the pathogenesis of POI. This paper begins with the pathogenesis of inflammatory aging and summarizes the relationship between inflammatory aging and premature ovarian insufficiency in a comprehensive way, as well as discussing the new diagnostic and therapeutic methods of POI.

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Section: Inflammatory Aging and Premature Ovarian Insufficiency (Poi)mentioning

confidence: 99%

Inflamm-Aging: A New Mechanism Affecting Premature Ovarian Insufficiency

Huang

et al. 2019

Journal of Immunology Research

132

View full text Add to dashboard Cite

show abstract

“…Dè s lors, proposer de mesurer l'AMH annuellement chez ces patientes afin de dé pister pré cocement l'IOP nous paraît excessif et difficilement applicable en pratique, sans parler du coû t et des consé quences parfois lourdes sur le plan psychologique. Il existe en revanche d'authentiques situations à risque d'IOP non iatrogè ne [62,63], parmi lesquelles la maladie d'Addison et les polyendocrinopathies auto-immunes mé ritent une mention particuliè re. Curieusement, l'AMH et le CFA restent un certain temps normaux, alors qu'une insuffisance thé cale est dé jà patente, avec en particulier baisse des androgè nes et é lé vation pré fé rentielle de la LH.…”

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