Instruments to assess quality of life in people with mental health problems: a systematic review and dimension analysis of generic, domain- and disease-specific instruments

Krugten, Frédérique C. W. van; Feskens, K.; Busschbach, Jan J. V.; Roijen, Leona Hakkaart-van; Brouwer, Werner

doi:10.1186/s12955-021-01883-w

Cited by 17 publications

(19 citation statements)

References 65 publications

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“…The importance in doing so may be emphasised by the fact that sound and concise instruments, capable of adequately capturing important life domains impacted by mental health problems, are currently lacking [ 26 ]. Instruments like the MHQoL, therefore, can facilitate broadening the application of HTA to the field of mental health in a way that the benefits of mental health interventions are indeed captured.…”

Section: Discussionmentioning

confidence: 99%

Psychometric evaluation of the Mental Health Quality of Life (MHQoL) instrument in seven European countries

Enzing

Krugten²,

Sabat³

et al. 2022

Health Qual Life Outcomes

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Introduction To make efficient use of available resources, decision-makers in healthcare may assess the costs and (health) benefits of health interventions. For interventions aimed at improving mental health capturing the full health benefits is an important challenge. The Mental Health Quality of Life (MHQoL) instrument was recently developed to meet this challenge. Evaluating the pyschometric properties of this instrument in different contexts remains important. Methods A psychometric evaluation of the MHQoL was performed using existing international, cross-sectional data with 7155 respondents from seven European countries (Denmark, France, Germany, Italy, Portugal, The Netherlands, Portugal and the United Kingdom). Reliability was examined by calculating Cronbach’s alpha, a measure of internal consistency of the seven MHQoL dimensions, and by examining the association of the MHQoL sum scores with the MHQoL-VAS scores. Construct validity was examined by calculating Spearman’s rank correlation coefficients between the MHQoL sum scores and EQ-5D index scores, EQ-VAS scores, EQ-5D anxiety/depression dimension scores, ICECAP-A index scores and PHQ-4 sum scores. Results The MHQoL was found to have good internal consistency for all seven countries. The MHQoL sum score and the MHQoL-VAS had a high correlation. Spearman’s rank correlation coefficients were moderate to very high for all outcomes. Conclusion Our results, based on data gathered in seven European countries, suggest that the MHQoL shows favourable psychometrical characteristics. While further validation remains important, the MHQoL may be a useful instrument in measuring mental health-related quality of life in the Western European context.

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Section: Discussionmentioning

confidence: 99%

Psychometric evaluation of the Mental Health Quality of Life (MHQoL) instrument in seven European countries

Enzing

Krugten²,

Sabat³

et al. 2022

Health Qual Life Outcomes

Self Cite

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“…While there is evidence that these issues may be valid in depression, concordance between generic HRQoL measures and clinical measures has been shown to reduce with severity ( 109 ). Partly in response to these concerns, there has been increased focus on measurement of wellbeing and quality of life in mental health ( 110 ), but to date, there exists no mental health domain-specific preference-based measure that has been sufficiently validated that it can be recommended as an alternative to the EQ-5D or the SF-6D. In the absence of such a measure, the quality of the evidence used to inform EQ-5D generated utility data is of particular importance, and extensive sensitivity testing of utility values is imperative.…”

Section: Discussionmentioning

confidence: 99%

Economic evaluation of interventions for treatment-resistant depression: A systematic review

Hannah

Walsh²,

Jopling³

et al. 2023

Front. Psychiatry

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BackgroundThe extraordinarily high prevalence of treatment-resistant depression (TRD), coupled with its high economic burden to both healthcare systems and society, underscore how critical it is that resources are managed optimally to address the significant challenge it presents.ObjectiveTo review the literature on economic evaluation in TRD systematically, with the aim of informing future studies by identifying key challenges specific to the area, and highlighting good practices.MethodsA systematic literature search across seven electronic databases was conducted to identify both within-trial and model-based economic evaluations in TRD. Quality of reporting and study design was assessed using the Consensus Health Economic Criteria (CHEC). A narrative synthesis was conducted.ResultsWe identified 31 evaluations, including 11 conducted alongside a clinical trial and 20 model-based evaluations. There was considerable heterogeneity in the definition of treatment-resistant depression, although with a trend for more recent studies to use a definition of inadequate response to two or more antidepressive treatments. A broad range of interventions were considered, including non-pharmacological neuromodulation, pharmacological, psychological, and service-level interventions. Study quality as assessed by CHEC was generally high. Frequently poorly reported items related to discussion of ethical and distributional issues, and model validation. Most evaluations considered comparable core clinical outcomes – encompassing remission, response, and relapse. There was good agreement on the definitions and thresholds for these outcomes, and a relatively small pool of outcome measures were used. Resource criteria used to inform the estimation of direct costs, were reasonably uniform. Predominantly, however, there was a high level of heterogeneity in terms of evaluation design and sophistication, quality of evidence used (particularly health state utility data), time horizon, population considered, and cost perspective.ConclusionEconomic evidence for interventions in TRD is underdeveloped, particularly so for service-level interventions. Where evidence does exist, it is hampered by inconsistency in study design, methodological quality, and availability of high quality long-term outcomes evidence. This review identifies a number of key considerations and challenges for the design of future economic evaluations. Recommendations for research and suggestions for good practice are made.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=259848&VersionID=1542096, identifier CRD42021259848.

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“…The fact that existing quality of life measurements fall short of accurately capturing comprehensive output and the value of benefits of mental healthcare interventions.. 24 A multidimensional psychometric measurement is very essential to ensure that the tools utilized are comprehensive and psychometrically sound to properly quantify and value these benefits of QOL. In literature variety of instruments in existence to measure QOL, in which some investigators, particularly apply a single domain while other investigators tap into a series of domains.…”

Section: Psychometric Measurements Of Qol In Depression Disordermentioning

confidence: 99%

Quality of life: concepts, needs, psychometric measurement, factors associated and treatment responsiveness in depression disorder

Sevak

Balamurugan²

2023

Int J Community Med Public Health

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Quality of life (QOL) is a multifaceted concept that warrants attention, especially in depression disorder. This review aimed to summarize the empirical evidence regarding concepts, needs, psychometric measurement, factors associated, and treatment responsiveness in depression disorder. The narrative review was conducted based on studies published in English databases from the last three decades to 2022 on the evidence from extensive electronic databases using PubMed, SCOPUS, PsychINFO, ScienceDirect, SpringerLink, and Google Scholar. The significant findings from books, journals and grey literature were also included. Based on relevant and significant facts the concepts were developed and evidence-based narrations were made under each concept to understand QOL in depression disorder. This review found a significant association between poorer QOL with the severity of depression and, its association with age of respondents, the intensity of the depressive symptoms, lower education, subjective perception of health, lower socio-economical status, and social support. The review signifies the needs and psychometric instruments of QOL in patients with depressive disorder. The review revealed that psychoeducation, multimodal and community-based lifestyle intervention, self-awareness and body-mind-spirit interventions, CBT, group therapy and mental health promotion intervention improved the QOL in depression disorder. The study concluded that QOL is a patient-centric approach, and should be involved as the standard measure of evaluating care outcomes, satisfaction, and cost-effectiveness through the incorporation of the various treatment approaches in clinical practice. Despite being an essential component QOL is received relatively little attention in depression disorder by clinicians and mental health professionals.

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Instruments to assess quality of life in people with mental health problems: a systematic review and dimension analysis of generic, domain- and disease-specific instruments

Cited by 17 publications

References 65 publications

Psychometric evaluation of the Mental Health Quality of Life (MHQoL) instrument in seven European countries

Psychometric evaluation of the Mental Health Quality of Life (MHQoL) instrument in seven European countries

Economic evaluation of interventions for treatment-resistant depression: A systematic review

Quality of life: concepts, needs, psychometric measurement, factors associated and treatment responsiveness in depression disorder

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