Instrumentation and methods for ion and reaction monitoring using a non-scanning rectilinear ion trap

Zhang, Chao; Chen, Huanwen; Guymon, Andrew J.; Wu, Guangxiang; Cooks, R. Graham; Ouyang, Zheng

doi:10.1016/j.ijms.2005.10.013

Cited by 19 publications

(20 citation statements)

References 23 publications

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“…While the V rf at the stability boundary is close to 342 V 0−p in our computations, they report an experimentally observed value close to 260 V 0−p . However, the results reported in our simulations compares favorably with the experimental results reported by Zhang et al [32] for a slightly different geometry of the RIT which has y 0 = 3.8 mm. Fig.…”

Section: Stability Region For the Rit-ssupporting

confidence: 89%

“…The rectilinear ion trap (RIT) mass spectrometer, invented by Cooks and co-workers [19,32], has a 6-electrode mass analyzer with four planar rectangular electrodes (arranged symmetrically around the central axis) constituting the central section and two flat electrodes, facing the central section, forming the endcaps. The geometry of the RIT is a simplification of the geometry of the linear ion trap (LIT) [3], which has a four hyperbolic rod central section and two electrically isolated segments of the central section acting as the endcap electrodes.…”

Section: Introductionmentioning

confidence: 99%

“…To increase the fragmentation efficiency Collings [4] introduced extra electrodes in between the circular rods of the LIT and Michaud et al [18] used two different rod diameters to study its effect on the trap performance. For the RIT, Ouyang et al [19] and Zhang et al [32] have stretched the central section in one direction to obtain improved resolution in mass spectra for resonance ejection experiments. Similar results were reported in a stretched RIT in resonance ejection experiments by [27] using their 4-electrode RIT [26].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Numerical observation of preferred directionality in ion ejection from stretched rectilinear ion traps

Krishnaveni

Verma

Menon

et al. 2008

International Journal of Mass Spectrometry

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Section: Stability Region For the Rit-ssupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Numerical observation of preferred directionality in ion ejection from stretched rectilinear ion traps

Krishnaveni

Verma

Menon

et al. 2008

International Journal of Mass Spectrometry

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“…Significantly better performance has been achieved using RITs compared to CITs of similar dimension operated under similar conditions. As expected, many of the advantages of the RIT are the result of its increased trapping capacity and improved injection efficiency [15][16][17][18].…”

mentioning

confidence: 59%

Novel linear ion trap mass analyzer composed of four planar electrodes

Song

et al. 2006

J. Am. Soc. Mass Spectrom.

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A novel linear ion trap mass analyzer was developed using just four elongated planar electrodes, mounted in parallel, and employing an RF potential for ion trapping in the radial and axial directions. Mass analysis was achieved using the mass-selective instability scan with ion ejection in the radial direction. The performance of this new device was characterized in comparison with the 6-electrode rectilinear ion trap (RIT) from which it is derived. The 4-electrode trap gives optimum performance in an asymmetric geometry, just like the original optimized 6-electrode RIT. The strong RF fringing fields at the ends of the RF rods account for axial ion trapping without use of extra electrodes or an axial DC voltage. Field calculations and simulations have been carried out to study the trapping potential inside RITs with various configurations. Demonstrated capabilities include analysis of externally injected ions with mass resolution in excess of 1000 and a mass/charge range of 650 Th as well as tandem mass spectrometry capabilities. The geometric simplicity and performance characteristics of the 4-electrode RIT make it particularly attractive in the development of next generation miniaturized mass spectrometers.

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“…As with any ion trap, there are different operation modes for the RIT. For instance, (1) either single-phase or two-phase RF can be applied to the x and y pair electrodes to confine ions in the x-y plane, (2) either DC or AC signals can be applied to the z pair electrodes to confine the trapped ions along the z axis, (3) ions can be ejected either radially through the slits in the x pair of electrodes or axially through the holes in the z pair of electrodes [48,49]. For the modeled RIT, the half distance between the x pair electrodes is 5.0 mm, the half distance between y pair electrodes is 4.0 mm, the length of x and y pairs of electrodes is 40.0 mm.…”

Section: Ms Performance Of a Rectilinear Ion Trapmentioning

confidence: 99%

Ion trajectory simulation for electrode configurations with arbitrary geometries

Cooks

Ouyang

et al. 2006

J. Am. Soc. Mass Spectrom.

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A multi-particle ion trajectory simulation program ITSIM 6.0 is described, which is capable of ion trajectory simulations for electrode configurations with arbitrary geometries. The electrode structures are input from a 3D drawing program AutoCAD and the electric field is calculated using a 3D field solver COMSOL. The program CreatePot acts as interface between the field solver and ITSIM 6.0. It converts the calculated electric field into a field array file readable by ITSIM 6.0 and ion trajectories are calculated by solving Newton's equation using Runge-Kutta integration methods. The accuracy of the field calculation is discussed for the ideal quadrupole ion trap in terms of applied mesh density. Electric fields of several different types of devices with 3D geometry are simulated, including ion transport through an ion optical system as a function of pressure. Ion spatial distributions, including the storage of positively charged ions only and simultaneous storage of positively/negatively charged ions in commercial linear ion traps with various geometries, are investigated using different trapping modes. Inelastic collisions and collision induced dissociation modeled using RRKM theory are studied, with emphasis on the fragmentation of n-butylbenzene inside an ideal quadrupole ion trap. The mass spectrum of 1,3-dichlorobenzene is simulated for the rectilinear ion trap device and good agreement is observed between the simulated and the experimental mass spectra. Collisional cooling using helium at different pressures is found to affect mass resolution in the rectilinear ion trap.

show abstract

Instrumentation and methods for ion and reaction monitoring using a non-scanning rectilinear ion trap

Cited by 19 publications

References 23 publications

Numerical observation of preferred directionality in ion ejection from stretched rectilinear ion traps

Numerical observation of preferred directionality in ion ejection from stretched rectilinear ion traps

Novel linear ion trap mass analyzer composed of four planar electrodes

Ion trajectory simulation for electrode configurations with arbitrary geometries

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