Background.
Therapeutic EUS (t-EUS) is increasingly adopted in clinical practice of tertiary referral centres; however, little is known about Radiation Exposure (RE) metrics and Diagnostic Reference Limits.
Methods.
Kerma-Area Product (KAP [Gy·cm2]), Air Kerma and Fluoroscopy Time were retrospectively evaluated for all consecutive t-EUS procedures performed in San Raffaele Institute between 2019-2021. For EUS-guided Choledochoduoenostomies (EUS-CDS) and Gastroenterostomies (EUS-GE) an equal number of ERCPs + metal stenting and Duodenal Stentings were included for comparison.
Results.
141 t-EUS procedures were retrieved (49% pancreatic cancer, 38% peripancreatic fluid collections). EUS-CDS (N=44) were mainly performed fluoroless, while ERCPs required a significantly higher RE (KAP=25 [17-55], p<0.0001). Fluid collection drainage (EUS-FCD) with Lumen Apposing stents (LAMS, N=26) were performed fluoroless, while EUS-FCD with double-pigtail plastic stents (DPPS, N=28) required higher RE (KAP=23 [13-45]). EUS-guided gallbladder drainage (EUS-GBD, N=6) required scarce RE (KAP=9 [3-21]) for coaxial DPPS placement. EUS-GE (N=27) required higher RE than Duodenal Stenting (KAP=44 [28-88] versus 29 [19-46], p=0.03). EUS-guided Hepatico-Gastrostomies (EUS-HGS, N=10) had the highest RE amongst t-EUS procedures (KAP=81 [49-123]). Procedure complexity or intervening complications were evaluated and resulted in higher RE within each procedure.
Conclusions.
t-EUS procedures have different RE (p<0.000001). EUS-Choledochoduodenostomy, Gallbladder Drainage and Fluid Collection Drainage with LAMS can be performed with no-to-mild radioscopy, unlike standard alternatives. However, radioscopy remains essential in case of technical difficulties or complications. EUS-Gastroenterostomy and EUS-Hepaticogastrostomy involve a high RE. Endoscopists involved in t-EUS might experience a RE superior to category standards, claiming for increased awareness and personalized preventive measures.