“…Although most of the studies were conducted in the USA 9, 10, 12, 13, 15-17, 21-32, 34-38, 42, 43, 45, 49-57, 61, 62, 64, 65, 67, 73 and Canada, 19,44,46,66,68 twenty-one studies evaluated populations in other countries including five in Austria, 39,[58][59][60]63 five in Australia/New Zealand, 20,31,70,71,74 four in Germany, 11,14,47,48,58 three in Iran, 33,40,41 two in the UK, 20,69 and one each in Belgium 72 and Korea. 73 Nearly all of the included studies were single-arm observational studies (Table 1).…”