Insomnia in Diabetic Hemodialysis Patients

Abstract

Background: Insomnia is one of the most common problems in dialysis patients, and likely to contribute impairment in quality of life, which has a positive correlation with patients’ survival. In diabetic patients, morbidity and mortality are substantially higher than in the nondiabetic counterparts, and also the incidence of sleep disturbances. However, there is no means to predict sleep disturbance in the dialysis patients especially in diabetics. To define the prevalence and risk factors for insomnia in diabetic patients on hemodialysis, we undertook a cross-sectional multicenter study. Methods: Eighty-two diabetic patients (50 men/32 women, aged 58.7 ± 9.23 years) on maintenance hemodialysis for more than 6 months from 12 different hospitals were enrolled. The demographic data, subjective symptoms, depression scale, and insomnia were assessed by questionnaires, and lean body mass, BMI, Kt/V, subjective global assessment, nursing assessment score (NAS), and biochemical parameters were examined. Results: The number of patients with and without insomnia were 56 and 26, respectively, which amounted to 68.2% for insomnia. NAS (28.1 ± 3.81 vs. 30.8 ± 2.88, p = 0.002), serum albumin concentration (3.82 ± 0.44 vs. 4.09 ± 0.36 g/dl, p = 0.008), and depression scale (25.2 ± 12.1 vs. 18.9 ± 10.3, p = 0.025) were significantly different between them. Patients with insomnia were older (60.5 ± 9.0 vs. 56. 1 ± 9.60 years, p = 0.053) and felt pain (38.5 vs. 15.3%, p = 0.06) more frequently than those without insomnia. The scale of depression was correlated with NAS (r = –0.455, p < 0.001) and the serum albumin concentration was correlated with NAS (r = 0.337, p = 0.002). NAS, age, and serum albumin concentration were the major risk factors for insomnia in logistic regression analysis. Conclusion: The prevalence of insomnia in diabetic hemodialysis patients was 68.2%. Age, nutritional status, and depression were the major risk factors for sleep disturbance in diabetic patients.

Sleep quality in patients on maintenance hemodialysis and peritoneal dialysis

“…[182530] In our study, however, age was independently associated with only one of the sleep quality domains, “day dysfunction due to sleepiness.” Although age is found to be independently associated with sleep quality, this association may be, at least in part, mediated by the presence of comorbid diseases, less physical activity, and nutritional status in older patients. [1831–33] We also found female gender an independent predictor of sleep latency. Female gender was associated with poor sleep quality in one other study,[26] but the other one found an association between male gender and sleep quality.…”

Depression and Insomnia in Patients on Maintenance Hemodialysis

“…This findings revealed a significant association between Depression and Insomnia (r=0.334, P=0.000. Han found more than 68% patients on MHD having insomnia and most of them having depressive symptoms 15 . This finding is similar with present study.)…”

Development and effect of a rational‐emotive‐behaviour‐therapy‐based self‐management programme for early renal dialysis patients

“…Furthermore, due to the biochemical process of dialysis and the inadequacy of current dialysis therapy, anaemia, sleep disturbance and restless leg syndrome are also common (O'Sullivan & McCarthy, 2009). In fact, insomnia is one of the most common problems dialysis patients experience, and it has been found to negatively affect patient survival and also to reduce quality of life (Han et al, 2002;Pierratos & Hanly, 2011).…”