Insomnia and hypertension: a systematic review

Jarrin, Denise C.; Alvaro, Pasquale K.; Bouchard, Marc–André; Jarrin, Stephanie; Drake, Christopher L.; Morin, Charles M.

doi:10.1016/j.sleep.2017.11.430

Cited by 25 publications

(34 citation statements)

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“…In a systematic review of 64 studies, a strong correlation was found between insomnia and hypertension. [ 20 ] To explain this association, a biological model of the dysfunction of hypothalamic-pituitary-adrenal axis has been proposed, but the mechanism is still unclear. [ 21 ] However, psychological factors, including emotional distress, and biological factors, including excessive activity of arousal-related neural pathways, may be involved.…”

Section: Introductionmentioning

confidence: 99%

Oriental herbal medicine for insomnia in the elderly with hypertension

et al. 2018

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Background:Hypertension and insomnia are common diseases in the elderly. Oriental herbal medicine has been widely used in East Asia, and it has been considered as a promising alternative to conventional pharmacotherapy because of its efficacy in geriatrics. Moreover, since oriental herbal medicine acts on multiple targets, it may affect both hypertension and insomnia at the same time, which can reduce the risk of polypharmacy in this population. This systematic review will assess the efficacy and safety of oriental herbal medicine in the elderly with both insomnia and hypertension.Methods:Thirteen databases including English, Chinese, Korean, and Japanese databases will be searched from their inception to August 2018. We will include randomized controlled trials assessing oriental herbal medicine for insomnia in the elderly with hypertension. The methodological quality of the included studies will be evaluated using the Cochrane Collaboration's risk of bias tool, and confidence in the cumulative evidence will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation instrument.Results:This review will provide evidence to determine the efficacy and safety of oriental herbal medicine in the elderly with both insomnia and hypertension.Conclusions:Our results will help clinicians and health policy makers take informed decisions regarding the use of oriental herbal medicine in the elderly. It will also provide evidence-based oriental herbal medicine data for elderly patients suffering from multiple diseases and their families.

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Section: Introductionmentioning

confidence: 99%

Oriental herbal medicine for insomnia in the elderly with hypertension

et al. 2018

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“…Respondents are asked to rate, on a 4-point scale (0-3), their usual chances of dozing off or falling asleep while engaged in eight different activities. An ESS >10 points suggest the presence of excessive daytime sleepiness and results were evaluated in 5 groups [lower normal (0-5), higher normal (6-10), mild excessive (11)(12), moderate excessive (13)(14)(15), and severe excessive sleepiness (16)(17)(18)(19)(20)(21)(22)(23)(24)]. 12 ISI is a seven-item questionnaire designed as a short screening tool for insomnia.…”

Section: Methodsmentioning

confidence: 99%

“…A 5-point Likert scale is used to rate each item (for example, 0=no problem; 4=very serious problem), giving a total score ranging from 0 to 28. The total score is interpreted as follows: lack of insomnia (0-7); subthreshold insomnia (8)(9)(10)(11)(12)(13)(14); moderate insomnia (15)(16)(17)(18)(19)(20)(21); and severe insomnia (22-28). 13 PSQI is a self-report that evaluates sleep quality in 1 month period.…”

Section: Methodsmentioning

confidence: 99%

Relationship of Non-Dipper and Reverse-Dipper Pattern with Sleep Quality in Normotensive Patients

Yalım

Yalım²

2020

J Sleep Med

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It has been observed in many different populations that circadian blood pressure (BP) patterns have a significant impact on cardiovascular (CV) results. Important predictors of CV morbidity and mortality are known as non-dipper (ND) and reverse-dipper (RD) BP pattern. RD and ND patterns are frequently encountered in many normotensive patients in daily practice. Methods: The purpose of this study is to evaluate the frequency and quality of sleep, especially in normotensive young individuals, by using sleep questionnaires and to evaluate their relationship with poor BP patterns. A total of 195 normotensive patients (68 dippers, 63 ND, and 65 RD) were enrolled into this cross-sectional study. The insomnia severity index (ISI), Epworth sleepiness scale (ESS), and Pittsburgh sleep quality index (PSQI) approved questionnaires were applied to evaluate the presence and severity of sleep disorders and to determine the patient's sleep quality. Results: When dipper and ND groups were compared, significant differences were observed in ISI, ESS, and PSQI (p<0.001). Then, the study patients were re-evaluated as dipper, ND, and RD groups and seen this significant difference continued (p<0.001). Also, the sleep time was significantly different between all groups of dipper (7.23±0.11 hours), ND (6.72±0.15 hours), and RD (5.79±0.11 hours) (p<0.001). In the correlation analysis, a significant inverse relationship was observed between sleep time and all survey results (p<0.05). Conclusions: RD and ND patterns are associated with sleep quality in healthy individuals. It is necessary to evaluate patients with RD and ND BP patterns in normotensive individuals in terms of sleep disorders in detail.

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“…A recently published systematic‐review pooled data from 64 clinical studies with diverse designs, including more than 740 000 adults (46.4% male) with insomnia to investigate the relationship between insomnia and hypertension . It was found that when insomnia is frequent, chronic, and accompanied with short sleep or objective indices of arousal, there is a robust link with hypertension.…”

Section: Studies On Insomnia Conducted Over the Last 2 Y Evaluating mentioning

confidence: 99%