Insilico Toxicity and Pharmacokinetics Tests -an Antitumor Drug
Shweta,
Hedgapure Mahesh,
Kvln Murthy
Abstract:Drug metabolism is a crucial aspect of medical practice and pharmacology, involving the transformation of drugs by various bodily systems to create compounds that are more easily eliminated from the body. Cytochrome P450 (CYP) enzymes, predominantly found in hepatocyte endoplasmic reticulum, play a central role in metabolizing numerous small molecule drugs through diverse oxidative and reductive biotransformations. The study of absorption, distribution, metabolism, and excretion (ADME) is integral to drug desi… Show more
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