Insights on Monkeypox Disease and Its Recent Outbreak With Evidence of Nonsynonymous Missense Mutation

Abstract

The 2022 monkeypox outbreak has created a new global health threat and pandemic. Monkeypox virus is a descendant of the genus Orthopoxvirus, producing a febrile skin rash disease in humans. Monkeypox is zoonotic transmitted and transmitted from human to human in several ways. Even though this disease is self-limited, it creates important community health worries due to its inconvenience and widespread complications. Herein, we discussed the up-to-date current situation of monkeypox regarding its epidemiology, clinical manifestations, current in-use therapeutics, necessary protective measures, and response to potential occurrences considering the recent pandemic. Also, in this review, a comparative genomic analysis of the recent circulating strains that have been recovered from various countries including, Egypt, USA, Spain, Japan and South Africa has been investigated.

Preparing for future outbreaks in Ghana: An overview of current COVID-19, monkeypox, and Marburg disease outbreaks

“…Monkeypox is a disease that occurs regularly and persistently in some African countries, 32 , 33 but until July 8, 2022, Ghana had not reported any confirmed cases of Monkeypox in humans. However, the Ghana Health Service announced the first confirmed cases of Monkeypox on July 8, 2022.…”