Insights into Prospects of Novel NSAID Prodrugs in the Management of
Gastrointestinal Toxicity: A Perspective Review
Rajat Goyal,
Sumeet Gupta,
Prabodh Sharma
et al.
Abstract:Non-steroidal anti-inflammatory drugs (NSAIDs) have a long history in the
healthcare system due to their therapeutic potential. These NSAIDs cause ulcerogenicity, stomach
pains, gastrointestinal hemorrhage, mucosa bleeding, and pancreatitis when used moderately
and consistently. With researchers, managing the aforementioned adverse effects therapeutically
is getting increasingly difficult. One method for creating NSAID moieties with low penetration
as well as ulcerogenic properties is the prodrug technique. Du… Show more
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