Insights into Antimicrobial and Anti-Inflammatory Applications of Plant Bioactive Compounds

Abstract

Plants have long been thought to contribute to health promotion due to their fiber and phenolic content, as well as their inherent biological potential. The bioactive derivatives of medicinal plants are a valuable resource in the fight against serious diseases all around the world. The present review focuses on the current state of knowledge on the usage and medicinal applications of plant bioactives. Issues concerning the effect of aromatic plant derivatives on human gut microbiota and their antimicrobial and anti-inflammatory potentials are discussed and worth further exploring.

Omics approaches in understanding the benefits of plant-microbe interactions

“…Additionally, plant-microbe interaction omics may offer novel therapeutic approaches for human health. Plant-derived antimicrobial, anti-inflammatory, or immunomodulatory compounds can be used to develop drugs or dietary supplements for microbiome diseases or dysfunction (Mitropoulou et al, 2023 ). Some plant-associated microbes produce bioactive metabolites that kill human pathogens and promote the growth of commensal bacteria (Kandasamy and Kathirvel, 2023 ).…”

Biodiversity of Skin Microbiota as an Important Biomarker for Wound Healing

“…However, the misuse and overuse of antibiotics have led to the generation of drug-resistant pathogens [ 119 , 120 ], and antimicrobial resistance concerns were reported as one of the top global public health threats facing humanity by the World Health Organization [ 121 ]. Therefore, exploring alternative and cost-effective antimicrobials based on traditional plant-based medicines has become prominent [ 122 ]. Plant-based antimicrobials (e.g., essential oils, herbal extracts) have been determined as effective alternatives to accelerate the natural wound healing process, as well as tissue regeneration in the wound area due to the broad range of natural bioactive compounds contained in herbs [ 123 , 124 , 125 ].…”

Phytochemical analysis, GC–MS profile and determination of antibacterial, antifungal, anti-inflammatory, antioxidant activities of peel and seeds extracts (chloroform and ethyl acetate) of Tamarindus indica L

“…In recent times, antimicrobial, anti-inflammatory and anti-oxidative properties having biological molecules extracted from plant sources are gaining much attention ( Ain et al, 2023 , Bagewadi et al, 2019 , Brindhadevi et al, 2023 , Kumar et al, 2023 , Mitropoulou et al, 2023 , Shaukat et al, 2023 ). For example, anti-inflammatory agents are used to treat COVID-19 as well as neuroinflammation and also have anti-carcinogenic as well as diabetes-control properties ( Kumar et al, 2023 , Merecz-Sadowska et al, 2023 ; Perico et al, 2022 ).…”