Abstract:Predictions for a near end of the pandemic by the World Health Organization should be interpreted with caution. Current evidence indicates that the efficacy of a fourth dose of classical mRNA vaccines (BT162b2 or mRNA-1273) is low and short-lived in preventing SARS-CoV-2 infection in its predominant variant (Omicron). However, its efficacy is high against severe symptomatic infection, hospitalization and death. The new vaccines being introduced are bivalent and active against the Omicron variants. Potential ne… Show more
“…Increasing overall vaccine coverage is greatly needed, particularly as new variants continue to emerge. 9 , 10 There is an urgent need to increase coverage in children specifically, given the protective benefits and the broader epidemiologic dividend of vaccinating children. 11 Unfortunately, in a recent survey of 1847 US adults, only 62% thought COVID-19 vaccines were safe for children ages 12 to 17, 55% thought they were safe for children ages 5 to 11, and 48% thought they were safe in very young children (0-4).…”
This qualitative analysis sought to explore factors that influenced parent/guardian intentions to vaccinate their children against SARS-CoV-2 in San Francisco, California, USA in order to inform San Francisco Department of Public Health’s (SFDPH) youth vaccine rollout program. 30-minute, semi-structured telephone interviews were conducted with parents and guardians in either Spanish or English. Respondents shared their perspectives on vaccinating their children against SARS-CoV-2. Interviews were conducted over the telephone and recorded on Zoom. Participants (n = 40) were parents/guardians responding on behalf of their adolescent children (age 13+) and parents/guardians identified from the SFDPH COVID-19 testing database who tested for SARS-CoV-2 within the last 2 weeks. Interviews were conducted, audio recorded, transcribed, translated into English as appropriate, and rapidly analyzed in REDCap according to matrix analysis methodology to develop parent study themes. Perspectives on child vaccination were then explored through thematic analysis. Three themes were identified from the thematic analysis: (1) parental desires for children to return to school safely, (2) unclear messaging and information on COVID-19 prevention and vaccination, and (3) consideration of child’s desires or opinions on receiving the vaccine. This study highlights specific factors influencing parent/guardian decisions on whether to vaccinate their children against SARS-CoV-2. The analysis also illustrates a potential role for children to play in influencing household vaccine decision-making.
“…Increasing overall vaccine coverage is greatly needed, particularly as new variants continue to emerge. 9 , 10 There is an urgent need to increase coverage in children specifically, given the protective benefits and the broader epidemiologic dividend of vaccinating children. 11 Unfortunately, in a recent survey of 1847 US adults, only 62% thought COVID-19 vaccines were safe for children ages 12 to 17, 55% thought they were safe for children ages 5 to 11, and 48% thought they were safe in very young children (0-4).…”
This qualitative analysis sought to explore factors that influenced parent/guardian intentions to vaccinate their children against SARS-CoV-2 in San Francisco, California, USA in order to inform San Francisco Department of Public Health’s (SFDPH) youth vaccine rollout program. 30-minute, semi-structured telephone interviews were conducted with parents and guardians in either Spanish or English. Respondents shared their perspectives on vaccinating their children against SARS-CoV-2. Interviews were conducted over the telephone and recorded on Zoom. Participants (n = 40) were parents/guardians responding on behalf of their adolescent children (age 13+) and parents/guardians identified from the SFDPH COVID-19 testing database who tested for SARS-CoV-2 within the last 2 weeks. Interviews were conducted, audio recorded, transcribed, translated into English as appropriate, and rapidly analyzed in REDCap according to matrix analysis methodology to develop parent study themes. Perspectives on child vaccination were then explored through thematic analysis. Three themes were identified from the thematic analysis: (1) parental desires for children to return to school safely, (2) unclear messaging and information on COVID-19 prevention and vaccination, and (3) consideration of child’s desires or opinions on receiving the vaccine. This study highlights specific factors influencing parent/guardian decisions on whether to vaccinate their children against SARS-CoV-2. The analysis also illustrates a potential role for children to play in influencing household vaccine decision-making.
“…Previously, several articles have been published on the impact of COVID-19 on environmental factors, where multiple study showed a significant correlation between climatic indicators like humidity, temperature, due point, wind speed rainfall and SARS-CoV-2 induced fatality. 27. , 28.…”
“…[19][20][21][22] However, the ongoing risks posed by emergence of newer and rapidly evolving variants of SARS-CoV-2 (Alpha, Beta, Gamma, Delta, Epsilon, Omicron to name a few) have raised concerns against the management practices and demand timely research to combat the situation. [23][24][25][26][27][28] Therefore, the significance of this review lies in unraveling the intricate interplay between SARS-CoV-2 and cancer and present an arena of scientific inquiry holding potential ramifications for clinical practice and therapeutic strategies. By synthesizing the available knowledge, the objectives of this review are to provide a comprehensive understanding of the challenges and opportunities that have arisen at the juncture of COVID-19 and cancer, ultimately guiding future research directions and shaping the evolution of cancer care in a postpandemic landscape.…”
The coronavirus disease 2019 (COVID‐19) pandemic brought about unprecedented challenges to global healthcare systems. Among the most vulnerable populations are cancer patients, who face dilemmas due to their compromised immune systems and the intricate interplay with the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus. This comprehensive review delves into the multifaceted relationship between COVID‐19 and cancer. Through an analysis of existing literature and clinical data, this review unravels the structural intricacies of the virus and examines its profound implications for cancer patients, thereby bridging the knowledge gap between virology and oncology. The review commences with an introduction regarding the COVID‐19 pandemic and cancer. It then transitions into a detailed examination of the SARS‐CoV‐2 virus and its variants such as Alpha (PANGO lineage B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2), and Omicron (B.1.1.529 lineage). Subsequently, an insightful analysis of the impact of COVID‐19 on major cancer types (viz., Lung, Colon, Brain, and gastrointestinal cancer) is elaborated. Finally, the therapeutic avenues, oncological care, and management are discussed. The nexus between COVID‐19 and cancer adds a layer of complexity to patient care, emphasizing the importance of tailored approaches for those grappling with both conditions. Amid the landscape defined by the evolving viral strains, this review navigates through the multifaceted implications of COVID‐19 on cancer patients and underscores the significance of integrating virology and oncology.
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