Insight into the phytochemical, biological, and in silico studies of Erythrina suberosa roxb.: A source of novel therapeutic bioactive products from a medicinal plant

Alamri, Abdulhakeem S.; Saleem, Hammad; Pervaiz, Irfan; Khurshid, Umair; Butt, Juwairiya; Chohan, Tahir Ali; Alhomrani, Majid; Locatelli, Marcello; Abidin, Syafiq Asnawi Zainal; Alqahtani, Yasir Nasser H; Rengasamy, Kannan R.R.; Mahomoodally, Mohamad Fawzi

doi:10.1016/j.fbio.2023.102429

Cited by 4 publications

(2 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Herbal remedies have been used to cure and prevent illness for thousands of years and are a promising source for the development of novel pharmaceuticals. [1,2] Plants possess a vast array of medicinally active molecules that are produced through distinct metabolic pathways; these compounds are attributed to their bioactive metabolites, which are extracted and responsible for their therapeutic effects. Thus, the urgent need for quick and accurate methods of checking plant extracts-especially food plants-for biological activity is only going to increase.…”

Section: Introductionmentioning

confidence: 99%

“…This means they are responsible for the creation of half of all currently available medications. Herbal remedies have been used to cure and prevent illness for thousands of years and are a promising source for the development of novel pharmaceuticals [1,2] . Plants possess a vast array of medicinally active molecules that are produced through distinct metabolic pathways; these compounds are attributed to their bioactive metabolites, which are extracted and responsible for their therapeutic effects.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Detailed Phytochemical Evaluation of a Locally Endemic Species (Campanula baskilensis) by LC‐MS/MS and Its In‐Depth Antioxidant and Enzyme Inhibitory Activities

Yilmaz,

Cakir,

Izol

et al. 2023

Chemistry & Biodiversity

View full text Add to dashboard Cite

The importance of bioactive plant species in the scientific world is increasing day by day. The relationship between health and traditional‐modern life, promotes the creation of new value‐added natural products. This is the first research to conduct a bioactivity and chemical composition analysis of Campanula baskilensis species, which belongs to the medicinally important genus Campanula L (Campanulaceae). The aim of the current study is to quantitatively investigate the phytochemical contents of aerial and root parts of different C. baskilensis extracts (ethanol, methanol, and water) by LC‐MS/MS and to evaluate their total phenolic and flavonoid contents, antioxidant and enzyme inhibitory activities. Remarkably, LC‐MS/MS results revealed that, high amounts of quinic acid (53.6 mg/g aerial‐MeOH extract), fumaric acid (6.3 mg/g aerial‐H2O extract, 2.5 mg/g root‐ H2O extract), protocatechuic acid (11.4 mg/g aerial‐H2O extract), vanilic acid (1.4 mg/g aerial‐EtOH extract), quercetin‐3‐O‐rutinoside (rutin) (2.3 mg/g aerial‐EtOH extract), hesperetin 7‐rutinoside (hesperidin) (2.0 mg/g aerial‐EtOH extract), kaempferol‐3‐O‐rutinoside (nicotiflorin) (5.5 mg/g aerial‐EtOH extract) were detected in the extracts of the species. Considering the bioactivity tests performed on C. baskilensis extracts, aerial‐H2O extract showed significant activity in all antioxidant assays. However, ethanol extracts of root and aerial parts exhibited the highest activities in all enzyme inhibitory tests.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%