Insight into the Epigenetics of Kaposi’s Sarcoma-Associated Herpesvirus
Anusha Srivastava,
Ankit Srivastava,
Rajnish Kumar Singh
Abstract:Epigenetic reprogramming represents a series of essential events during many cellular processes including oncogenesis. The genome of Kaposi’s sarcoma-associated herpesvirus (KSHV), an oncogenic herpesvirus, is predetermined for a well-orchestrated epigenetic reprogramming once it enters into the host cell. The initial epigenetic reprogramming of the KSHV genome allows restricted expression of encoded genes and helps to hide from host immune recognition. Infection with KSHV is associated with Kaposi’s sarcoma, … Show more
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