Insight into Oral Biofilm: Primary, Secondary and Residual Caries and Phyto-Challenged Solutions

Chenicheri, Smitha; Usha, R.; Ramachandran, Rajesh; Thomas, Vinoy; Wood, Andrew T.

doi:10.2174/1874210601711010312

Cited by 76 publications

(61 citation statements)

References 136 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, opportunistic pathogens Fusobacterium or Leptotrichia, whose abundance we found to be elevated in the Active RAS cohort, have been described as part of the normal oral microbiota [29,30]. Fusobacterium nucleatum has been previously connected to incidence of dental caries and periodontitis [31,32]. Furthermore, F. nucleatum can spread to the intestinal tract and is tightly associated with colorectal carcinoma development [33].…”

Section: Discussionmentioning

confidence: 76%

Oral Microbiota Composition and Antimicrobial Antibody Response in Patients with Recurrent Aphthous Stomatitis

et al. 2019

View full text Add to dashboard Cite

Recurrent aphthous stomatitis (RAS) is the most common disease of the oral mucosa, and it has been recently associated with bacterial and fungal dysbiosis. To study this link further, we investigated microbial shifts during RAS manifestation at an ulcer site, in its surroundings, and at an unaffected site, compared with healed mucosa in RAS patients and healthy controls. We sampled microbes from five distinct sites in the oral cavity. The one site with the most pronounced differences in microbial alpha and beta diversity between RAS patients and healthy controls was the lower labial mucosa. Detailed analysis of this particular oral site revealed strict association of the genus Selenomonas with healed mucosa of RAS patients, whereas the class Clostridia and genera Lachnoanaerobaculum, Cardiobacterium, Leptotrichia, and Fusobacterium were associated with the presence of an active ulcer. Furthermore, active ulcers were dominated by Malassezia, which were negatively correlated with Streptococcus and Haemophilus and positively correlated with Porphyromonas species. In addition, RAS patients showed increased serum levels of IgG against Mogibacterium timidum compared with healthy controls. Our study demonstrates that the composition of bacteria and fungi colonizing healthy oral mucosa is changed in active RAS ulcers, and that this alteration persists to some extent even after the ulcer is healed.

show abstract

Section: Discussionmentioning

confidence: 76%

Oral Microbiota Composition and Antimicrobial Antibody Response in Patients with Recurrent Aphthous Stomatitis

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The S-layer present at the outermost cell surface of some Lactobacillus species is responsible for cell surface hydrophobicity 95 . Vadillo-Rodríguez et al, studied on the cell surface hydrophobicity of two species of Lactobacillus, they concluded that in a low ionic strength suspension, both Lactobacillus strains show higher initial deposition rates to hydrophobic glass than to hydrophilic glass, whereas in a high ionic strength suspension no clear influence of cell surface hydrophobicity on adhesion is observed 65,96,97,121 .…”

Section: Cell Surface Hydrophobicity: Attachment Ofmentioning

confidence: 99%

“…So far, various EPS-producing Lactobacillus species have been identified such as L. casei, L. acidophilus, L. brevis, L. curvatus, L. delbrueckii subsp. bulgaricus, L. helveticus, L. rhamnosus, L. plantarum, and L. johnsonii 65,97,98 .…”

Section: Exopolysaccharide Produced By Lactobacillusmentioning

confidence: 99%

“…It is known from over 50 years that dental caries causes by the fermentation of food material, these food fermented by certain acid producing bacteria. Two types of bacteria are involved in tooth decay; which is: mutans streptococci and Lactobacillus species these both can produce acid during the metabolism of sugar fermentation 15,74,94,97 . When these bacteria produced acid in the dental plaque on tooth surface they readily diffuse in all directions in the mouth.…”

Section: Mechanisms Of Dental Caries Formationmentioning

confidence: 99%

See 1 more Smart Citation

Untitled

2019

IJPSR

View full text Add to dashboard Cite

Dental caries is an infective serious transmittable bacterial disease characterized by a multi-factorial pathology. Main players in the etiology of this disease are cariogenic bacteria, fermentable carbohydrates, a susceptible tooth, the host, and the time. It is still one of the most common disease worldwide. Biological factor such as cariogenic bacteria plays an important role in dental caries initiation, progression as well as tooth decay. Previous studies suggested that the main pathogenic bacteria are Streptococcus mutans and Lactobacillus. Consequently, Lactobacillus is considered the second most cariogenic bacteria of oral flora. It is not the caries initiator but plays an important role in caries progression. Most of the previous studies were quantitative, so till now, researchers not know about the specific species of Lactobacillus which are directly associated with dental caries progression. Some species-level identification studies suggested that the most common Lactobacillus species are L. gasseeri, L. fermentum, L. vaginalis and L. casei which were predominantly reported at the most of the oral sites, i.e. saliva, tongue, carious lesion, dental plaque, etc. and maybe plays the main role in caries progression. The present review spotlights the role, pathogenicity of Lactobacillus in dental caries and their ecology in the oral cavity.

show abstract

“…Both caries and periodontal disease can lead to tooth loss. Thus, dental biofilm plays a fundamental role in the pathogenic process of oral diseases (Chenicheri, R, Ramachandran, Thomas, & Wood, ; Wolff, Frese, Maier‐Kraus, Krueger, & Wolff, ). This way, the prevention and treatment of caries and periodontal disease benefit from antimicrobial strategies (Nazar Majeed, Philip, Alabsi, Pushparajan, & Swaminathan, ; Serrano, Escribano, Roldán, Martín, & Herrera, ; Wang et al, ).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial activity of copaiba oil (Copaifera ssp.) on oral pathogens: Systematic review

Diefenbach

Muniz

Oballe

et al. 2017

Phytotherapy Research

View full text Add to dashboard Cite

Copaifera ssp. produces an oil-resin that presents antiinflammatory, antitumor, antiseptic, germicidal, antifungal, and antibacterial activity. This systematic review aimed to analyze the antimicrobial action of Copaiba oil against oral pathogens, when compared to that of control substances. A search on Medline/PubMed, LILACS, SciELO, EMBASE, and SCOPUS databases were performed up to March 2017. To be included, the studies needed to perform any antimicrobial activity essay, using copaiba oil and a control substance. The antimicrobial effect of each substance, in each study, was extracted. Eleven studies were included, and several copaiba species were used. All studies showed that copaiba oil, regardless of its species, presented a bactericidal and/or bacteriostatic effect in in vitro analyzes. Only one study showed that the antimicrobial effect of the Copaifera officinalis was similar to the one found in chlorhexidine. A higher risk of bias was detected in most of the included studies. The studies demonstrated that the antimicrobial activity of copaiba oil, in most cases, is lower than chlorhexidine, which is considered the gold standard. However, there is great potential against oral bacteria. Further high quality studies are warranted in order to assess the efficacy of copaiba oil on oral pathogens.

show abstract

Insight into Oral Biofilm: Primary, Secondary and Residual Caries and Phyto-Challenged Solutions

Abstract: Abstract:Introduction:

Cited by 76 publications

References 136 publications

Oral Microbiota Composition and Antimicrobial Antibody Response in Patients with Recurrent Aphthous Stomatitis

Oral Microbiota Composition and Antimicrobial Antibody Response in Patients with Recurrent Aphthous Stomatitis

Untitled

Antimicrobial activity of copaiba oil (Copaifera ssp.) on oral pathogens: Systematic review

Contact Info

Product

Resources

About