Insight into myocardial ischemia-reperfusion injury from the perspective of ferroptosis
Xia Huang,
Yanni Wang,
Xiangrong Cui
et al.
Abstract:Myocardial ischemia-reperfusion injury (MIRI) most frequently happens in acute myocardial infarction (AMI) when rapid reperfusion is utilized to save the ischemia myocardium. MIRI is the main contributing of poor healing in AMI and is related to high mortality and disability rates around the worldwide. Currently, there is no effective precautionary measure for MIRI. Ferroptosis is a novel regulated cell death characterized by iron overload and reactive oxygen species (ROS) accumulation, which lead to death mem… Show more
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