Abstract:The inside cover picture shows a DNA-targeting artemisinin-netropsin drug conjugate docked into d(CGCGAATTCGCG) duplex DNA (PDB code: 1D86). The conjugate combines a trioxane warhead and a minor groove binder joined through a phenyl linker. For more details, see the Communication by Paul M. O'Neill et al. on p. 709 ff.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.