Insecticidal Activity of Thymoquinone and Related Compounds AgainstCulex quinquefasciatus(Diptera: Culicidae)

Abstract

Insecticides based on botanical sources have taken on increased attention due to differing modes of action from current insecticides in use and the view that they may be environmentally friendly. Thymoquinone, a component in the essential oil of incense cedar heartwood, has been shown to have insecticidal action against adult mosquitoes. This study evaluated relative toxicities of thymoquinone, selected derivatives of thymoquinone, hydroquinone, and arbutin to determine if any had similar or better activity. The intrinsic toxicities of hydroquinone and thymohydroquinone were not significantly different from thymoquinone, while libocedrol and arbutin were significantly less toxic.

Thymoquinone (2-Isopropyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects

“…Thymoquinone (2-Isopropyl-5-methyl-1, 4-benzoquinone) is the bioactive constituent of the volatile oil of black cumin ( Nigella sativa L.) seeds that has been extensively utilised traditionally in Middle East and Southeast Asian countries owing to its various health promoting capacities (Majdalawieh et al, 2017). It has been widely analyzed for its broad range of medicinal and pharmacological activities including but not limited to anti-inflammatory (Taka et al, 2018), anti-oxidant (Armutcu et al, 2018), antihistaminic (Kanter et al, 2006), antitumor (Singh et al, 2018), analgesic (Amin and Hosseinzadeh, 2016), anti-Alzheimer’s (Cascella et al, 2018), hepatoprotective, neuroprotective (Noorbakhsh et al, 2018), renoprotective, histone protein modulator (Rasheed et al, 2018), insecticidal (Scott et al, 2017), anti-ischemic (Bouhlel et al, 2017), Leishmanicidal (Mahmoudvand et al, 2015), radioprotective effects (Akyuz et al, 2017). TQ has also been clinically tested for a diverse kind of ailments like arthritis, diabetes, hypercholesterolemia etc.…”