Insecticidal activity, mammalian cytotoxicity and mutagenicity of an ethanolic extract from <i>Nerium oleander</i> (Apocynaceae)

El-Shazly, Mohamed; El-Zayat, Emad; Hermersdörfer, H.

doi:10.1111/j.1744-7348.2000.tb00020.x

Cited by 19 publications

(15 citation statements)

References 10 publications

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“…Nerium oleander L. is a small evergreen tree of 2-5 m in height with a wide geographical and ecological distribution (Fu et al 2005), and its certain parts are used as medicinal materials in Chinese folk medicine (Ji 1999). This plant possesses cardiotonic, antibacterial, antileprotic, anti-inflammatory, anticancer, and antiplatelet aggregation activities, insecticidal activity, mammalian cytotoxicity, and depressants of the central nerve system (EI-Shazly et al 2000;Fu et al 2005). Various compounds have been reported in connection with these biological activities, such as cardenolides (oleanderin, neriantin, adynerin, deacetyloleanderin, neriifolin), triterpenoidal saponins, oleanderol, rutin, dambonitol in leaves; odorosides (A, B, D, F, G, H, K) in barks; triterpene, steroidal cardenolide, volatile oil, stearic acid, oleic acid in roots; and gitoxigenin, uzarigenin, strospeside, odoroside H in flowers (Ji 1999;EI-Shazly et al 2000;Fu et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Endophytic fungi from Nerium oleander L (Apocynaceae): main constituents and antioxidant activity

Huang

Cai

Hyde

et al. 2007

World J Microbiol Biotechnol

130

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Diverse endophytic fungi exist within plant aerial tissues, with a global estimate of up to a million undescribed species. These endophytes constitute a rich bio-resource for exploration to discover new natural products. Here we investigate fungal endophytes associated with a medicinal plant, Nerium oleander L. (Apocynaceae). A total of 42 endophytic fungal strains were isolated from the host plant. Total antioxidant capacity, xanthine oxidase inhibitory activity, antimicrobial activity, and total phenolic content (TPC) were evaluated for 16 representative fungal cultures grown in improved Czapek's broth and for the host plant. The total antioxidant capacities and phenolic contents of the fungal cultures ranged from 9.59 to 150.79 lmol trolox/100 mL culture, and from 0.52 to 13.95 mg gallic acid/100 mL culture, respectively. The fungal culture of an endophytic strain Chaetomium sp. showed the strongest antioxidant capacity, contained the highest level of phenolics, and to some extent inhibited xanthine oxidase activity with an IC 50 value of 109.8 lg/ mL. A significant positive correlation was found between antioxidant capacity and TPC in the tested samples. Most of the endophytic fungal cultures tested have a wide range of antimicrobial activities, which were not very strong, but much better than those of the host plant. The major bioactive constituents of the fungal cultures were investigated using LC-ESI-MS and GC-MS, and preliminary identification detected phenolics (e.g. phenolic acids and their derivatives, flavonoids) and volatile and aliphatic compounds. This study shows that the endophytic fungi isolated from N. oleander can be a potential antioxidant resource.

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Section: Introductionmentioning

confidence: 99%

Endophytic fungi from Nerium oleander L (Apocynaceae): main constituents and antioxidant activity

Huang

Cai

Hyde

et al. 2007

World J Microbiol Biotechnol

130

View full text Add to dashboard Cite

show abstract

“…Morsy et al 1998a recorded a good larvicidal activity with acetone and chloroform extracts of lemon grass (Symbopogon citratus), santonica (Artemisia cinae) and pomegranate (Punica granatum) against 3rd instar larvae of C. albiceps. Extracts of Nerium oleander had effective against C. albiceps fly (El-Shazly et al 2000). Morsy et al 1998b provided that the volatile oils of American wormseed (Chenopodium ombrosioides) and thyme (Thymus vulgaris) was effective against 3rd instar larvae of Lucilia sericata.…”

Section: Discussionmentioning

confidence: 98%

“…Most studies on medical and veterinary pests conducted on mosquitoes, ticks and mites, while few studies curried out on myiasis producing flies (Morsy et al 1998a, b;Mazyad et al 1999El-Shazly et al 2000and El-Khateeb et al 2003. Morsy et al 1998a recorded a good larvicidal activity with acetone and chloroform extracts of lemon grass (Symbopogon citratus), santonica (Artemisia cinae) and pomegranate (Punica granatum) against 3rd instar larvae of C. albiceps.…”

Section: Discussionmentioning

confidence: 98%

The efficacy of some wild medicinal plant extracts on the survival and development of third instar larvae of Chrysomyia albiceps (Wied) (Diptera: Calliphoridae)

Abdel-Shafy¹,

El-Khateeb²,

Soliman

et al. 2009

Trop Anim Health Prod

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Four crude wild plants extract of Artemisia herba-alba Asso, Artemisia monosperma Del., Euphorbia aegyptiaca Boiss. and Francoeuria crispa (Forsk.) extracted with four successive solvents; hexane, diethyl ether, ethyl acetate and ethanol were evaluated against the third instar larvae of Chrysomyia albiceps using dipping and thin film techniques. In dipping technique, larvae were immersed in the concentrations of plant extracts for 30 seconds. However, in thin film technique, larvae were exposed to thin layer from each plant extract in the Petri-dishes. Results showed that all extracts had toxic effects on larvae in both two treatments. Hexane and diethyl ether extracts of A. herba-alba and ethyl acetate extract of A. monosperma recorded the highest effect in both two treatments. Ethanol extracts of E. aegyptiaca and A. monosperma were the highest in dipping and thin film treatments, respectively. In dipping treatment, most plant extracts revealed extending effect on pupae especially while in thin film treatment most larvae which succeeded to develop to pupae produced normal flies. Deformed pupae were only recorded with the high concentration of diethyl extracts of A. herba-alba. Hexane, diethyl ether and ethyl acetate extracts of F. crespa only produced low percentages of deformed flies. Histological examination conducted on larvae confirmed that extracts in thin film treatment penetrated to the gut and destroyed its epithelial cells and wall. It concluded that the crude extracts of the four tested plants can be used in controlling of C. albiceps larvae while hexane extracts of E. aegyptiaca, A. herba-alba and A. monosperma are considered the most promising plant preparations against the larvae by using thin film technique.

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“…Plant-derived materials are expected to be a possible alternative insecticide to synthetic chemicals in controlling the flies (Pandian and Manoharan, 1995). Many studies gave good results when evaluated some plant extracts in control of medical and veterinary insects such as C. albiceps (Morzy et al, 1998a: El-Shazly, et al, 2000 and Lucilia sericata (Mazyad et al, 1999). Several studies have also looked at the possibility of using plant extracts in the control of eggs, larvae, pupae and adults of Musca domestica (Issakul et al, 2004;Malik et al, 2007).…”

Section: Open Access Research Articlementioning

confidence: 99%

Evaluation of Extract from Sweet Flag Rhizome for Biological Activity against House Fly

Meenakshisundaram¹,

Harikrishnan²,

Rani³

et al. 2014

IJAVST

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The problem of house fly has become more acute everywhere especially in poultry and piggery farms. They act as potential vector for many viral, bacterial, helminthic and protozoan diseases and as nuisance pests. The control of fly is very much effected by the use of synthetic organic insecticides. These drugs, even though efficacious, can be detrimental to the mankind and environment and also lead to the development of resistance. Hence, in the present study, the larvicidal and adulticidal effect of Vasambu (Acorus calamus) were evaluated against the housefly. For larvicidal evaluation, the test drug, Vasambu at different concentrations (1 per cent, 2 per cent, 3 per cent and 4 per cent) was sprayed on the dung sample containing 100 number of 3rd instar larvae of house fly. The larvae were observed daily for the development of pupae and subsequent emergence of adult fly. Lowest fly emergence (Highest mortality of larvae) was observed in 4 per cent and 3 per cent treatment groups and they differed highly significantly (P<0.01) with rest of the groups. There is no significant difference between 4 and 3 per cent treated groups and between the 1 per cent, 2 per cent and control groups. For adulticidal effect, Vasambu at different concentrations (2, 4 and 6 per cent) were used as bait (consisting of rice bran, jaggery and Vasambu). Fifty number of house fly pupae were placed in a fly rearing chamber. Immediately after the emergence of the first fly, the Vasambu bait was kept inside the fly rearing chamber and observed daily for the mortality. Highest fly mortality was observed in bait incorporated with 6 per cent concentration and it differed significantly (P<0.05) with control and 2 per cent treated treatment groups. However, there is no significant difference between 6 per cent and 4 per cent treatment groups and between 4 per cent, 2 per cent and control groups.

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Insecticidal activity, mammalian cytotoxicity and mutagenicity of an ethanolic extract from Nerium oleander (Apocynaceae)

Cited by 19 publications

References 10 publications

Endophytic fungi from Nerium oleander L (Apocynaceae): main constituents and antioxidant activity

Endophytic fungi from Nerium oleander L (Apocynaceae): main constituents and antioxidant activity

The efficacy of some wild medicinal plant extracts on the survival and development of third instar larvae of Chrysomyia albiceps (Wied) (Diptera: Calliphoridae)

Evaluation of Extract from Sweet Flag Rhizome for Biological Activity against House Fly

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