The climate plays a significant role either directly or indirectly in crop production. Changing climate poses serious challenges to food safety and food security worldwide. Plant physiology is affected by this factor in vegetable production, and quality of the produce is changed by the various a biotic factor. Biotechnological interventions are the need of the day to produce enough quality food to feed the world's ever-increasing population. Conventional breeding is no doubt a significant sphere of agriculture for improving vegetable production; however, advanced approaches, like genetic engineering and molecular techniques for genetic improvement, can play a considerable role in mitigating the food shortage. Breeders may make great efforts to create varieties that can withstand great stress. The challenge is to produce varieties that can withstand high temperatures and low inputs, high rusticity, and biotic and abiotic stresses of climate change. Keywords: Climate change, abiotic and biotic stress, genetics improvement, conventional breeding, quality enhancement