Insect Antifeedant Potent Halogen Substituted Phenyl Chalcones

Abstract

Some 2′,3′,4′-trichlorophenyl chalcones [(E)-1-(2,3,4-trichlorophenyl)-3-(substituted phenyl)-2-propen-1-ones] have been synthesised using sulfated Titania catalyzed solvent-free aldol condensation between 2,3,4-trichloroacetophenone and substituted benzaldehydes. The purities of synthesised chalcones were checked by their analytical, physical and spectroscopic data reported in literature. The insect antifeedant activities of these chalcones have been studied using 4 th instar larvae Achoea Janata L by castor leaf disc bio-assay method. The chloro substituted chalcones shows significant insect antifeedant activity.

Insect Antifeedant Potential of Xanthohumol, Isoxanthohumol, and Their Derivatives

“…63 According to the literature, good antifeeding activity was also observed for compounds with a naphthalene substituent 64 and chalcones with electron acceptor groups in ring A. 65,66 The objective of our work was to obtain hop flavonoid compounds and their derivatives of diverse relatively simple chemical structures and to evaluate their antifeedant activity. For the biological tests we have chosen two major prenylated hop flavonoids, xanthohumol (14) and isoxanthohumol (6), and an isoxanthohumol derivative without the prenyl and methyl groups, naringenin (5), a flavonoid that is commonly found in citrus fruits.…”

“…Among the prenyl flavanones isolated from Tephrosia apollinea L., the most active antifeedants proved to be compounds with a dihydrofuran ring . According to the literature, good antifeeding activity was also observed for compounds with a naphthalene substituent and chalcones with electron acceptor groups in ring A. , …”

Sulfated Titania (TiO2‐SO42−) as an Efficient Catalyst for Organic Synthesis: Overarching Review from 2000 to 2021

“…Thirunarayanan et al [59] studied the preparation of phenyl chalcone from the aldol condensation reaction of 2',3',4'trichloroacetophenone and substituted aldehydes using TiO 2 -SO 4 2À under microwave irradiation (Scheme 3). The insect antifeedant activities of the titled chalcones have been examined.…”