Insect Antifeedant and Ixodicidal Compounds from Senecio adenotrichius

Abstract

Nine eremophilane sesquiterpenes 1 - 9, two flavonoids 11 and 12, and two known pirrolizidine alkaloids 13 and 14, were isolated from Senecio adenotrichius DC. Their structures were elucidated on the basis of spectroscopic data and by comparison with previously reported spectroscopic data of similar compounds. Compounds 5, 7, and 9 have not been previously reported as natural products. The antifeedant activity of these compounds was tested against Spodoptera litoralis and Myzus persicae. Eremophilanes 1, 3, and 8 were strong antifeedants to M. persicae, and 1 and 8 to Spodoptera littoralis. Their ixodicidal activity was tested against the tick Hyalomma lusitanicum, with eremophilanes 1, 3, and 8, being strong ixodicidal agents.

Antiparasitic Properties of Cantharidin and the Blister Beetle Berberomeloe majalis (Coleoptera: Meloidae)

“…The extracts and CTD were effective ixodicidal agents with similar effective doses (Table 5). CTD and CTD-rich extracts had LD 50 concentrations seven times more potent than the positive control, nootkatone [56] but had similar LD 90 values.…”

“…For each test, three replicates with 20 larvae each were used. Larval mortality was checked after 24 h of contact with the treated cellulose in the environmental conditions described [56], using a binocular magnifying glass. The mortality data shown have been corrected with respect to the control according to Schneider–Orelli’s formula.…”

“…b Lethal doses to give 50% and 90% mortality (95% Confidence Limits). c From Ruiz–Vázquez et al [56].…”

Biocidal Potential and Chemical Composition of Industrial Essential Oils from Hyssopus officinalis, Lavandula × intermedia var. Super, and Santolina chamaecyparissus

“…The eggs were kept under the same environmental conditions until hatched. Larvae (4 – 6 weeks old) were used for the bioassays as previously described by Ruiz‐Vásquez et al . The larvicidal activity data are presented as percentage of mortality corrected according to Schneider–Orelli 's formula.…”

Insect Antifeedant Components of Senecio fistulosus var. fistulosus—Hualtata

“…The most frequent chemical groups found in the non-alkaloidal fraction of Senecio are eremophilane-type sesquiterpenes of the furanoeremophilane and eremophilanolide type [1]. Some of these compounds have insect antifeedant, acaricidal, fungicidal, cytotoxic, phytotoxic, antioxidant, anti-inflammatory, and antimicrobial effects [1,2,3,4,5,6] and have been proposed as being an important part of Senecio defense [1,2,3,4,5].…”