Inpatient rehabilitation improves functional capacity, peripheral muscle strength and quality of life in patients with community-acquired pneumonia: a randomised trial

José, Anderson; Corso, Simone Dal

doi:10.1016/j.jphys.2016.02.014

Cited by 57 publications

(64 citation statements)

References 31 publications

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“… 3 Pneumonia is also a common reason for hospital readmission, particularly among older adults, who often experience a functional decline during the index admission. 4 , 5 , 6 , 7 , 8 Studies have identified an inverse association between functional status and risk of hospital readmission. 9 , 10 , 11 , 12 In addition, there is a growing body of literature on the detrimental effects of acute care hospitalization on functional independence.…”

Section: Introductionmentioning

confidence: 99%

Variation in Acute Care Rehabilitation and 30-Day Hospital Readmission or Mortality in Adult Patients With Pneumonia

et al. 2020

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Key Points Question Is the amount of physical and occupational therapy received by patients with pneumonia associated with 30-day hospital readmission or death? Findings In this cohort study of 30 746 patients with pneumonia or influenza-related conditions discharged from 12 acute care hospitals in western Pennsylvania, there was a significant inverse association between the amount of therapy received and the risk of 30-day hospital readmission or death. Meaning In this study, the amount of therapy received by patients with pneumonia or influenza-related conditions in the acute care setting was associated with decreases in the risk of 30-day hospital readmission or death.

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Section: Introductionmentioning

confidence: 99%

Variation in Acute Care Rehabilitation and 30-Day Hospital Readmission or Mortality in Adult Patients With Pneumonia

et al. 2020

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“…13 Until recently, studies showed that an integrated program of physical therapy during hospitalization could improve physical and functional performance in patients with pneumonia. 11,14 For patients who have severe pneumonia and stay in bed for a long time, hospitol acquired muscle weakness and muscle atrophy frequently occur. After discharge, the most common complications of patients with acute respiratory distress syndrome are exercise restriction and decline of life quality, which can last for 5 years.…”

Section: Discussionmentioning

confidence: 99%

“…Meanwhile, We also referred to data based on community-acquired pneumonia patients, which previously reported by Anderson J and Simone DC. 11 We estimate a 35% improvement in ADL score between the pulmonary rehabilitation group and control group with a two-sided test size of 5% and power of 80%. 27 eligible participants were required per study arm.…”

Section: Sample Sizementioning

confidence: 99%

A Randomized Controlled Study of Muscle Training Exercise Based Pulmonary Rehabilitation on Activity of Daily Living in Patients with Coronavirus Disease 2019

Zhao

Wang

Xue

et al. 2020

Preprint

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Abstract Background: Hospitalized patients with Coronavirus Disease 2019 (COVID-19) pneumonia showed a severve loss of muscle mass and strength over admission. Therefore, early physical interventions might be conducive to prevent disability and fasten recovery. Methods: We designed a prospective, randomized controlled trial to identify the effectiveness and safety of pulmonary rehabilitation based on muscle exercise in COVID-19 patients. The study was conducted between February 7th and March 31st 2020 in Union Hospital. Patients were randomly assigned to the pulmonary rehabilitation exercise group or the control group. Primary outcome was improvement of activity of daily living (ADL). Secondary outcome was changes of muscle strength assessed by manual muscle test (MMT) and arterial blood gas analysis. Length of hospital staying (LOS) and adverse events related to physical activity were also observed.Results: A total of sixty patients were in analysis, and thirty patients were in PR group. Patients had a mean age of 54.43±10.57 years. A statistically and clinically significant increase in ADL was observed in PR group (75.00 [66.25,90.00] to 100.00 [100.00,100.00], p<0.001). We also found that the improvement of ADL was related to younger age and higher PaO2 (p<0.01). Both groups had MMT improvement and there was no statistical difference between groups. There was a significant increase in PaO2 (80.23±6.49 vs. 90.47±7.82, respectively, p<0.001) between two groups before discharge. There was no statically significant difference in LOS between study group and control group (p=0.62). None of these patients had severe complications during the study.Conclusions: The protocal of pulmonary rehabilitation based on muscle training exercise was feasible in COVID-19 patients and it might accelerate recovery in ADL as compared with the spontaneous recovery in the control group.Clinical Trial Registration: ChiCTR, ChiCTR2000032457. Registered 29 April 2020- Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj=52925.

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“…The effects of rehabilitation have been evaluated from various aspects, but there was no de nite conclusion. Some studies showed that early rehabilitation reduced LOS [15,16] in pneumonia, but another study showed that it would prolong LOS [7]. The effects of rehabilitation on mortality and readmission rates were also unclear [17,18].…”

Section: Discussionmentioning

confidence: 99%

Limited effect of rehabilitation for preventing a decrease in functional status after community-acquired pneumonia in elderly patients 

Chen¹,

Hara²,

Horita³

et al. 2020

Preprint

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Background: Functional status (FS) is often decreased after hospitalization in elderly community-acquired pneumonia (CAP) survivors. Rehabilitation has frequently been used to prevent decreased FS. This study was designed to evaluate the effect of rehabilitation for preventing decreased FS.Methods: This retrospective, observational study was conducted in two medical facilities from January 2016 to December 2018, and hospitalized CAP patients >64 years of age were enrolled. FS was assessed by the Barthel Index (BI) (range, 0–100, in 5-point increments) at admission and before discharge and graded into three categories: independent, BI 80–100; semi-dependent, BI 30–75; and dependent, BI 0–25. Multivariable analysis of factors contributing to decreased FS was conducted with two groups: with a decrease of at least one category (decreased group), or without a decrease of a category (maintained group). Then, the effect of rehabilitation was examined by propensity score analysis by adjusting factors contributing to decreased FS determined in the previous multivariable analysis. Results: The maintained group included 400 patients, and the decreased group included 138 patients. The decreased group had a high frequency of rehabilitation therapy (189 (47.3%) vs 104 (75.4%); p<0.001). Multivariable analysis showed that factors affecting FS were length of stay, aspiration pneumonia, age, and Pneumonia Severity Index (PSI) of category V (odds ratio 1.05, 95%CI 1.04–1.07; 2.66, 95%CI 1.58–4.49; 1.05, 95%CI 1.02–1.09; and 1.92, 95%CI 1.29-3.44; respectively). After adjusting for factors contributing to decreased FS, rehabilitation showed a limited effect in preventing a decreased FS in 166 matched pairs (p=0.327).Conclusions: The effect of rehabilitation was still unclear in CAP, and further research is warranted to find an effective way to conduct rehabilitation.

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Inpatient rehabilitation improves functional capacity, peripheral muscle strength and quality of life in patients with community-acquired pneumonia: a randomised trial

Abstract: ClinicalTrials.gov, NCT02103400.

Cited by 57 publications

References 31 publications

Variation in Acute Care Rehabilitation and 30-Day Hospital Readmission or Mortality in Adult Patients With Pneumonia

Variation in Acute Care Rehabilitation and 30-Day Hospital Readmission or Mortality in Adult Patients With Pneumonia

A Randomized Controlled Study of Muscle Training Exercise Based Pulmonary Rehabilitation on Activity of Daily Living in Patients with Coronavirus Disease 2019

Limited effect of rehabilitation for preventing a decrease in functional status after community-acquired pneumonia in elderly patients

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Inpatient rehabilitation improves functional capacity, peripheral muscle strength and quality of life in patients with community-acquired pneumonia: a randomised trial

Abstract: ClinicalTrials.gov, NCT02103400.

Cited by 57 publications

References 31 publications

Variation in Acute Care Rehabilitation and 30-Day Hospital Readmission or Mortality in Adult Patients With Pneumonia

Variation in Acute Care Rehabilitation and 30-Day Hospital Readmission or Mortality in Adult Patients With Pneumonia

A Randomized Controlled Study of Muscle Training Exercise Based Pulmonary Rehabilitation on Activity of Daily Living in Patients with Coronavirus Disease 2019

Limited effect of rehabilitation for preventing a decrease in functional status after community-acquired pneumonia in elderly patients&nbsp;

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Limited effect of rehabilitation for preventing a decrease in functional status after community-acquired pneumonia in elderly patients