volume 319, issue 3, PE540-E547 2020
DOI: 10.1152/ajpendo.00202.2020
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Abstract: Background:The adipocytokine resistin is released from epicardial adipose tissue (EAT). Plasma resistin and EAT deposition are independently associated with atrial fibrillation (AF). The EAT secretome enhances arrhythmia susceptibility and inotropy of human myocardium. Therefore, we aimed to determine the effect of resistin on the function of human myocardium and how resistin contributes to the pro-arrhythmic effect of EAT. Methods & Results: EAT biopsies were obtained from 25 cardiac surgery patients. Re…

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