Inorganic stereochemistry: Geometric isomerism in bis-tridentate ligand complexes

Juraj, Natalija Pantalon; Kirin, Srećko I.

doi:10.1016/j.ccr.2021.214051

Cited by 12 publications

(37 citation statements)

References 151 publications

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“…[ 53,54 ] The reported complexes mainly have ML 2 stoichiometry, and the bis‐1,2,3‐triazole ligands show a preference for formation of trans – fac isomers. [ 55 ]…”

Section: Resultsmentioning

confidence: 99%

Ferrocene conjugates linked by 1,2,3‐triazole and their Zn(II) and Cu(II) complexes: Synthesis, characterization and biological activity

Jakopec

Juraj

Brozović

et al. 2022

Applied Organom Chemis

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Ferrocene derivatives with mono‐ (8a–c) and bis‐1,2,3‐triazolyl (9 and 10a–13c) chelating groups were synthesized by regioselective copper(I)‐catalysed 1,3‐dipolar cycloaddition of terminal alkynes with ferrocene azides. Metal complexes of the ligands were prepared with Cu(II) and Zn(II) salts. Crystal structures of ligands 9 and 11a were determined, as well as the structures of complexes [Cu(8a)2](CF3SO3)2 (8aCu) and [Cu(8c)2(CH3OH)2](BF4)2 (8cCu). In addition to NMR and UV–Vis spectroscopy, the metal complexes were characterized by cyclic voltammetry. The cytotoxic effect of ferrocene conjugates and their Zn(II) and Cu(II) complexes was explored, and cell cycle analysis was performed. The complex [Cu(8c)2](CF3SO3)2 showed the most prominent and selective cytotoxicity on cervical carcinoma (HeLa), ovarian cancer (MES‐OV), non‐small cell lung cancer (A549) and breast carcinoma (MDA‐MB‐231) cells. This complex increased cell population in the S and G2/M phase of the cell cycle, which was accompanied by an increase of the cells present in the sub‐G0/G1 fraction.

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“…[ 53,54 ] The reported complexes mainly have ML 2 stoichiometry, and the bis‐1,2,3‐triazole ligands show a preference for formation of trans – fac isomers. [ 55 ]…”

Section: Resultsmentioning

confidence: 99%

Ferrocene conjugates linked by 1,2,3‐triazole and their Zn(II) and Cu(II) complexes: Synthesis, characterization and biological activity

Jakopec

Juraj

Brozović

et al. 2022

Applied Organom Chemis

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“…Namely, Cu( ii ) prefers trans – fac coordination that is best suitable for formation of octahedral complexes, while Zn( ii ) would be more prone to distortion towards a trigonal-prismatic geometry under formation of a cis – fac isomer. 33…”

Section: Resultsmentioning

confidence: 99%

“…6). 33 Complexes of achiral ligands form a racemic mixture, 52 while in the case of chiral ligands, diastereomers are formed. Another indication of cis – fac coordination is the upfield shift of the axial pyridine protons (red a and a*, as assigned by COSY NMR at −40 °C, Fig.…”

Section: Resultsmentioning

confidence: 99%

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Tuning the coordination properties of chiral pseudopeptide bis(2-picolyl)amine and iminodiacetamide ligands in Zn(ii) and Cu(ii) complexes

et al. 2022

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“…This arrangement may be contributed from more stable cis ‐form of 4a in the solid state. [ 25c,28 ] The FeN and NO bond lengths are very the same in 1 , 2 , 4a and 4b , and the linear FeNO arrangement (angles 175.56(18)° for 1 ; 175.05(19)° for 2 ) remains virtually unchanged upon methylation of the thiol in 1 to form 2 , or without bearing a pendant thiol/thioether in the secondary coordination sphere (angles 176.2(3)° for 4a ; 175.5(2)° for 4b ). The NO bond distances in 1 , 2 , 4a and 4b are comparable to that of a NO radical (1.15 Å).…”

Section: Resultsmentioning

confidence: 99%

Light‐induced NO release from iron‐nitrosyl‐thiolato complex: The role of noncovalent thiol/thioether

Chen

Lee

Chien

et al. 2023

J Chinese Chemical Soc

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Four low‐spin {FeNO}6 complexes, [Fe(NO)(PS2)(PS2H)] (1, PS2H2 = bis(2‐dimercaptophenyl)phenylphosphine) with a pendant thiol, [Fe(NO)(PS2)(PS2CH3)] (2) bearing a pendant thioether, and [Fe(NO)(PS2)(RPS)] (RH, 4a; RTMS, 4b) without the noncovalent thiol/thioether group are spectroscopically and structurally characterized. In comparisons of the νNO, absorption energy in UV/vis spectra and structural parameters from single X‐ray diffraction studies, the four iron‐nitrosyl‐thiolato compounds share similarity in electronic structure. Complex 1 with a pendant thiol leads to NO and HNO production upon exposure to the light. Photolysis of 2 bearing a pendant thioether only affords NO. Effective detection of HNO or NO from 1 or 2 is achieved by the employment of [MnIII(TMSPS3)(DABCO)]. In contrast, 4a and 4b show inertness toward visible‐light stimulus. Photolysis and having pendant thiol/thioether group play key roles in NO production from these iron‐nitrosyl‐thiolato complexes, that is, the Fe‐NO bond is weakened by exposure to light and the noncovalent SH of 1 or SCH3 of 2 can serve as an incoming ligand to interact with Fe atom, resulting in a transient with intramolecular [RS⋅⋅⋅Fe⋅⋅⋅NO] interaction (RH and CH3) which could facilitate NO dissociation.

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Inorganic stereochemistry: Geometric isomerism in bis-tridentate ligand complexes

Cited by 12 publications

References 151 publications

Ferrocene conjugates linked by 1,2,3‐triazole and their Zn(II) and Cu(II) complexes: Synthesis, characterization and biological activity

Ferrocene conjugates linked by 1,2,3‐triazole and their Zn(II) and Cu(II) complexes: Synthesis, characterization and biological activity

Tuning the coordination properties of chiral pseudopeptide bis(2-picolyl)amine and iminodiacetamide ligands in Zn(ii) and Cu(ii) complexes

Light‐induced NO release from iron‐nitrosyl‐thiolato complex: The role of noncovalent thiol/thioether

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