Inorganic–organic hybrid silica based tin(II) catalyst: Synthesis, characterization and application in one-pot three-component Mannich reaction

Three-component carbon-carbon bond-forming reactions for the synthesis of β-amino carbonyl compounds using maleic acid-catalyzed one-pot mannich-type reaction in ethanol

“…In analogy with reported mechanisms (YUE et al, 2009;LU and CAI, 2010;SHARMA et al, 2012;MOUSAVI et al, 2013), the following mechanism is proposed to explain the formation of product (Scheme 2). Maleic acid acts as an acid catalyst and facilitates the respective formation of imine (6) from aldehyde (2) and aniline (3) via removal of the water molecule.…”

An Eco-Friendly Protocol for Synthesis of β- aminoketones via Mannich Reaction Using Citric Acid: A Biodegradable Catalyst

“…β-amino carbonyl derivatives are found in a number of biologically active natural products [5]. The reported Mannich reactions have been catalyzed by various Lewis or Brønsted acid catalysts such as silica-supported AlCl 3 [6], CeCl 3 .7H 2 0 [7], NbCl 5 [8], BiCl 3 [9], CAN [10], HClO 4 -SiO 2 [11], Bi(OTf) 3 [12], Zn(OTf) 2 [13], ionic liquid [14][15][16][17], sulphamic acid [18][19][20], Fe(Cp) 2 PF 6 [21], Cu-nanoparticles [22], [RE(PFO) 3 ] [23], silica based tin(II) catalyst [24], PEG-SO 3 H [25] ZSM-5-SO 3 H [26], carbon based solid acid [27], polyaniline/SiO 2 [28], lipase [29], saccharose [30], heteroplyacid salts [31]. However, most of the reported methods for the Mannich reaction suffer from drawbacks such as long reaction times and harsh reaction conditions, toxicity, and difficulty in product separation, which limit its use in the synthesis of complex molecules.…”

Manganese phthalocyanine immobilized on silica gel: Efficient and recyclable catalyst for single-step oxidative esterification of aldehydes with alcohols

“…Thus, considering the above advantages and in continuation of our research work on designing recyclable heterogeneous catalytic systems [30][31][32][33][34][35][36] for various organic transformations, herein we report the single-step oxidative esterification of aldehydes with alcohols in presence of newly synthesized tetrakis-(2-methoxy-4-formylphenoxy)phthalocyaninato manganese(III) acetate complex immobilized on silica gel as recyclable catalyst using hydrogen peroxide as an oxidant.…”