Innovative Dual-Emitting Ratiometric Fluorescence Sensor for Tetracyclines Detection Based on Boron Nitride Quantum Dots and Europium Ions

Abstract

On account of the excessive residues and serious detriments, it is imminent to develop an efficient method to determine tetracyclines (TCs) for protecting human health. In this work, a novel ratiometric fluorescence sensor was constructed for TCs based on a powerful boron nitride quantum dot and europium ion (BNQD-Eu 3+ ) system. The blue-emitting BNQDs were synthesized via a facile hydrothermal route using boric acid and urea as precursors. When TCs were presented in the hybrid probe of BNQDs and Eu 3+ , blue fluorescence of BNQDs was quenched and red fluorescence of Eu 3+ was enhanced, which can be attributed to the inner filter effect, photo-induced electron transfer, as well as the antenna effect. Besides, it was confirmed that the proposed sensor possessed good detection limits of 0.019, 0.104, and 0.028 μM for tetracycline (TET), oxytetracycline, and doxycycline, respectively. Additionally, the results of BNQD-Eu 3+ -based sensing of TET in milk and beef samples showed an insignificant difference from those of liquid chromatography−mass spectrometry. Moreover, the BNQD-Eu 3+ -based test paper was successfully used in the easy and visual detection of TCs by the naked eyes, indicating the practical applicability of the sensor.

Naproxen release aspect from boron-doped carbon nanodots as a bifunctional agent in cancer therapy

“…4d), representing B-O and B-C groups. 33 Therefore, the B-OH bond at 193.20 eV indicated that boric acid could replace the original ligand and free boric acid appeared on the CDS surface. 29 The morphological and crystal structure of BCD was examined by using X-ray diffraction (XRD) and atomic force microscopy (AFM).…”

Sensitive and selective determination of tetracycline in milk based on sulfur quantum dot probes

“…The constant uorescence lifetime combined with the high quenching rate constant conrm the existence of SQE. [50][51][52] From the above discussion, it can be concluded that the quenching of SQDs by TC is mainly based on a combination of IFE and SQE.…”

A Review on van der Waals Boron Nitride Quantum Dots

“…For example, Jerome et al have synthesized BNQDs by the hydrothermal method by using such a nitrogen source and boric acid dissolved in ethanol/water as the boron source [77]. The same boron and nitrogen source were used by other research groups [78] for BNQDs synthesis. Another hydrothermal method was reported by Yao et al [79] for the fabrication of BNQDs with a high QY of 32.3%.…”

“…The ALP activity measurement was achieved in a linear range between 2 and 200 U L −1 with a low limit of detection of 0.8 U L −1 . Recently, Yang et al [78] reported an efficient method to determine tetracyclines (TCs) using ratiometric fluorescence sensors based on BNQDs and europium ion (Eu 3+ ) systems. This system worked as a probe that detected the quenching of blue fluorescence of BNQDs when introduced with TCs, while enhancing the red fluorescence of Eu 3+ .…”