Innovative antibacterial electrospun nanofibers mats depending on piezoelectric generation

Abstract

This paper introduces a new approach of testing piezoelectric nanofibers as antibacterial mat. In this work, both Polyvinylidene fluoride (PVDF) and PVDF embedded with thermoplastic polyurethane nanofibers are synthesized as nanofibers mat via electrospinning technique. Then, such mat is analyzed as piezoelectric material to generate electric voltage under different mechanical excitations. Furthermore, morphological and chemical characteristics have been operated to prove the existence of beta sheets piezoelectricity of the synthesized nanofibers mats. Then, the synthesized nanofibers surfaces have been cyclically stretched and exposed to bacteria specimen. It has been noticed that the generated voltage and the corresponding localized electric field positively affect the growth of bacteria and reduces the formation of K. penomenue samples bacteria colonies. In addition, the effect of both stretching frequency and pulses numbers have been studied on the bacteria count, growth kinetics, and protein leakage. Our contribution here is to introduce an innovative way of the direct impact of the generated electric field from piezoelectric nanofibers on the reduction of bacteria growth, without depending on traditional anti-bacterial nanoparticles. This work can open a new trend of the usability of piezoelectric nanofibers through masks, filters, and wound curing mats within anti-bacterial biological applications.

Production of Nanofibers by Blow Spinning from Polylactide Containing Propolis and Beeswax

“…Nanofibers can be produced from many other proteins and polymers using the proper voltage and suitable solvent and selecting the correct process parameters in electrospinning [8,9]. Fibers fabricated by electrospinning can also be given bacteriostatic properties [10][11][12][13]. However, the disadvantage of electrospinning is the high voltage and low efficiency of the process using a single nozzle, although there are ways to scale up and thus increase efficiency [14].…”

Innovative Electrospun Nanofiber Mats Based on Polylactic Acid Composited with Silver Nanoparticles for Medical Applications

“…These nanofibers find applications in various fields, including tissue engineering [15][16][17], filtration [18][19][20], energy storage [21,22], adsorbents [23][24][25], and drug delivery [26][27][28][29]. In recent years, electrospinning has also emerged as a promising method for producing antibacterial nanofibers due to their potential in combating microbial infections and their application in wound healing [30][31][32][33]. This technique offers numerous enticing possibilities, one of which involves the inclusion of drugs, functional fillers, or bioactive molecules within the core of electrospun fibers [34].…”

Innovative Electrospun Nanofiber Mats Based on Polylactic Acid Composited with Silver Nanoparticles for Medical Applications

“…These nanofibers find applications in various fields, including tissue engineering [15][16][17], filtration [18][19][20], energy storage [21,22], adsorbents [23][24][25] and drug delivery [26][27][28][29]. In recent years, electrospinning has also emerged as a promising method for producing antibacterial nanofibers due to their potential in combating microbial infections and their application in wound healing [30][31][32][33]. This technique offers numerous enticing possibilities, one of which involves the inclusion of drugs, functional fillers, or bioactive molecules within the core of electrospinning fibers [34].…”