Innovations in Ureteral Stent Technology

Forbes, Connor M.; Scotland, Kymora B.; Lange, Dirk; Chew, Ben H.

doi:10.1016/j.ucl.2018.12.013

Cited by 44 publications

(39 citation statements)

References 70 publications

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“…Consider to remove double-J stent for persistent and severe hematuria. For backache caused by urine return to kidney through the double-J stent, urinate in time and avoid activity leading to urine reflux (23). For aggravated hydronephrosis or mild urinary infection, drinking more water, alkalizing urine and taking susceptible antibiotics.…”

Section: Sickness Caused By Double-j Stent Retentionmentioning

confidence: 99%

Optimize the management of urological tube-related emergencies during the coronavirus disease 2019 (COVID-19) pandemic

Luan¹,

Zhang²,

Kai³

et al. 2021

Transl Androl Urol

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Background: To introduce and determine the value of optimized strategies for the management of urological tube-related emergencies with increased incidence, complexity and operational risk during the global spread of coronavirus disease 2019 .Methods: All emergent urological patients at Tongji Hospital, Wuhan, during the period of January 23 (the beginning of lockdown in Wuhan) to March 23, 2020, and the corresponding period in 2019 were recruited to form this study's COVID-19 group and control group, respectively. Tongji Hospital has the most concentrated and strongest Chinese medical teams to treat the largest number of severe COVID-19 patients. Patients in the control group were routinely treated, while patients in the COVID-19 group were managed following the optimized principles and strategies. The case incidence for each type of tube-related emergency was recorded. Baseline characteristics and management outcomes (surgery time, secondary complex operation rate, readmission rate, COVID-19 infection rate) were analyzed and compared across the control and COVID-19 periods.Results: The total emergent urological patients during the COVID-19 period was 42, whereas during the control period, it was 124. The incidence of tube-related emergencies increased from 53% to 88% (P<0.001) during the COVID-19 period. In particular, the incidence of nephrostomy tube-related (31% vs. 15%, P=0.027) and single-J stent-related problems (19% vs. 6%, P=0.009) increased significantly. The mean surgery times across the two periods were comparable. The number of secondary complex operations increased from 12 (18%) to 14 (38%) (P=0.028) during the COVID 19-period. The number of 2-week postoperative readmission decreased from 10 (15%) to 1 (3%) (P=0.049). No participants contracted during the COVID-19 period.Conclusions: Urological tube-related emergencies have been found to have a higher incidence and require more complicated and dangerous operations during the COVID-19 pandemic. However, the optimized management strategies introduced in this study are efficient, and safe for both urologists and patients.

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Section: Sickness Caused By Double-j Stent Retentionmentioning

confidence: 99%

Optimize the management of urological tube-related emergencies during the coronavirus disease 2019 (COVID-19) pandemic

Luan¹,

Zhang²,

Kai³

et al. 2021

Transl Androl Urol

View full text Add to dashboard Cite

show abstract

“…These problems can cause damage to the kidneys or their failure. There is not currently an ideal ureteric stent [64] since they are very favorable for the adhesion of microorganisms and subsequent biofilm formation. Biofilm clogs the stent and this leads to widespread infection and sepsis.…”

Section: Stentsmentioning

confidence: 99%

Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents

et al. 2019

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Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Consequently, conventional stents have to be removed operatively from the patient’s body, which presents a number of complications and can also endanger the patient’s life. Biodegradable stents disintegrate into basic substances that decompose in the human body, and no surgery is required. This review focuses on the specific use of stents in the human body, the problems of microbial biofilm, and possibilities of preventing microbial growth by modifying polymers with antimicrobial agents.

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“…Currently, ureteral stents of various construction are used, such as double‐J (DJ), double‐J 3D, grooved, spiral, loop‐tail, tail, dual‐durometer, and dangler stents. They are mainly made of polymeric biomaterials, less often metallic biomaterials 10‐15 . Ureteral stents that are most commonly used in the treatment of the upper urinary tract are made of polyurethane.…”

Section: Introductionmentioning

confidence: 99%

Assessment of encrustation and physicochemical properties of poly(lactide‐glycolide) ‐ Papaverine hydrochloride coating on ureteral double‐J stents after long‐term flow of artificial urine

et al. 2021

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Implantation of ureteral stents is associated with inconvenience for the patient, which is related to the natural ability of the ureter to contract. The most frequently used solution is the systemic administration of a diastolic drug, which has a relaxing effect on smooth muscle cells and decreases inconvenience. Current interdisciplinary research aimed at reducing the complications after the implantation of ureteral stents used in the treatment of upper urinary tracts with regard to infection, initiation of encrustation, and fragmentation of stents, and patient pain has not been resolved. This study presents the results of research regarding the impact of a biodegradable coating with the active substance on the physical and chemical properties of ureteral stents used in the treatment of the upper urinary tract. The surface of polyurethane double‐J stents was coated with poly(lactide‐glycolide) (PLGA) 85/15 loaded with papaverine hydrochloride (PAP) with diastolic properties. The coating for ureteral stents has been designed for short‐term implantation. The effect of the coating on the process of encrustation and PAP release by the dynamic in vitro model with artificial urine (AU) up to 30 days was evaluated. The influence of AU on the physical and chemical properties of ureteral stents was determined. As part of the study, surface structure and topography researches; chemical composition analyses using X‐ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, and wetting; and surface roughness studies of both PUR stents and coated stents were carried out. The proposed biodegradable PLGA+PAP coating is characterized by controlled drug release, while optimal physicochemical properties does not increase the encrustation process.

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Innovations in Ureteral Stent Technology

Cited by 44 publications

References 70 publications

Optimize the management of urological tube-related emergencies during the coronavirus disease 2019 (COVID-19) pandemic

Optimize the management of urological tube-related emergencies during the coronavirus disease 2019 (COVID-19) pandemic

Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents

Assessment of encrustation and physicochemical properties of poly(lactide‐glycolide) ‐ Papaverine hydrochloride coating on ureteral double‐J stents after long‐term flow of artificial urine

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