Innovations in the postoperative management of the third molar and use of biomaterials. A look at different studies

Abstract

The extraction of third molars, commonly known as wisdom teeth, is a common surgical procedure in young adults. Given the complexity of this process, different methods were explored to improve healing, including the use of bioactive materials and platelet-rich fibrin (PRF). Recent advances have shown that PRF, especially in its variants such as A-PRF and L-PRF, can significantly accelerate the healing of hard and soft tissues, and is useful in maintaining tissue volume after extraction. This biomaterial has proven to be effective in reducing pain, inflammation and promoting bone regeneration. However, studies on its effectiveness and direct comparisons with natural healing are varied and require more in-depth analysis. The present study evaluated the effectiveness of natural healing compared to the use of PRF, focusing on lower third molar surgeries. Through a longitudinal experimental design, meta-analysis and systematic reviews of the existing literature were performed to identify, compile and compare clinical outcomes between the use of PRF and conventional healing methods. The research highlighted the potential of PRF in improving postoperative management protocols and suggested future directions for research and clinical application of these biomaterials in dentistry and other medical disciplines