Innervation of the Periodontal Ligament in the Dog with Special Reference to the Morphology of Ruffini Endings.

Sato, Osamu; Maeda, Takeyasu; Kannari, Koichi; Kawahara, Ichiro; Iwanaga, Toshihiko; Takano, Yoshiro

doi:10.1679/aohc.55.21

Cited by 23 publications

(15 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This type of ending was observed only in the incisive papilla and is likely to correspond to the Ruffini-like endings described in ultrastructural studies of the anterior hard palate in the rat (Byers and Yeh, 1984;Chan and Byers, 1985b). Ruffini endings with the same appearance have been described for the periodontal ligament of rodents (Sato et al, 1992). The Ruffini ending has been identified as a slowly adapting type I1 mechanoreceptor (Chambers et al, 1972), but its precise role in the incisive papilla remains to be elucidated.…”

Section: Discussionsupporting

confidence: 71%

Innervation of the hard palate in the rat studied by anterograde transport of horseradish peroxidase conjugates

Arvidsson

Fundin

Pfaller

1995

J of Comparative Neurology

View full text Add to dashboard Cite

The innervation of the rat hard palate and the bordering part of the soft palate was studied after anterograde transport of horseradish peroxidase conjugated to wheat germ agglutinin (WGA-HRP) and to choleragenoid (B-HRP) in separate experiments. WGA-HRP labeling showed leakage from several types of nerve endings, whereas B-HRP did not. Both conjugates gave rise to heavy labeling of a variety of nerve endings. Intragemmal and, especially, perigemmal fibers were labeled in chemosensory corpuscles, which were most common in the medial wall of the incisive canal and in the most anterior part of the soft palate. Ruffini endings of different sizes were labeled in the incisive papilla. Other subepithelial endings forming elongated expanded profiles with medium- to large-caliber source fibers were most common in protruding parts of the palate. Labeled intraepithelial endings included Merkel endings, which were most frequent in the incisive papilla and the rugae. Other labeled profiles were medium-caliber afferents giving rise to irregular, beaded, and sometimes branched endings often located far superficially in the epithelium. Such endings were present both within and between protruding parts of the palate. Fine-caliber intraepithelial endings were labeled almost exclusively in WGA-HRP experiments.

show abstract

Section: Discussionsupporting

confidence: 71%

Innervation of the hard palate in the rat studied by anterograde transport of horseradish peroxidase conjugates

Arvidsson

Fundin

Pfaller

1995

J of Comparative Neurology

View full text Add to dashboard Cite

show abstract

“…The present study reaches much the same conclusion as the previous study [12] on human teeth, which declared 31% of Ruffini-like receptors in the apical part of the tooth-related ligament. Another two studies on the canines of dogs and cats reported similar results by revealing the dense distribution of nerve fibres at the apical third of tooth [11,21]. It provides other evidence that the Ruffini endings are derived from myelinated axons.…”

Section: Discussionmentioning

confidence: 52%

“…Literature on a description of PDL innervation mainly covers papers on small animal PDL [6,7,[9][10][11][19][20][21][22]. Three types of nerve endings were identified under electron microscopy, including free nerve endings (originating from myelinated and unmyelinated nerve fibres), Ruffini-like endings (mostly found at the apical part of the PDL) and lamellated corpuscles [12,14,23].…”

Section: Discussionmentioning

confidence: 99%

“…It was demonstrated that the lingual PDL in hamster incisors was exclusively innervated by Ruffini endings by means of electron microscopy [10]. Neurofilament protein immunoreactive nerve fibres were also found to be densely distributed in the apical third of the PDL of dog incisors and canines [11]. It should be stressed that existing evidence is usually based on animal studies.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Histomorphological study of myelinated nerve fibres in the periodontal ligament of human canine

Huang

Corpas

Martens

et al. 2011

Acta Odontologica Scandinavica

View full text Add to dashboard Cite

show abstract

“…1A,B). Such an uneven distribution is reasonable because Ruffini endings are elicited when collagen fibers are stretched (Byers, 1985;Byers and Dong, 1989;Kannari, 1990;Kannari et al, 1991;Maeda, 1987;Maeda et al, 1990a;Sato et al, 1988Sato et al, , 1992.…”

Section: Morphology and Distribution Of The Periodontal Ruffini Endingsmentioning

confidence: 99%

Regeneration of periodontal Ruffini endings in adults and neonates

Wakisaka

Atsumi

2003

Microscopy Res & Technique

View full text Add to dashboard Cite

We reviewed the regeneration of periodontal Ruffini endings, primary mechanoreceptors in the periodontal ligament, following injury to the inferior alveolar nerve (IAN) in adult and neonatal rats. Morphologically, mature Ruffini endings are characterized by an extensive arborization of axonal terminals and association with specialized Schwann cells, called lamellar or terminal Schwann cells. Following injury to IAN in the adult, the periodontal Ruffini endings of the rat lower incisor ligament regenerate more rapidly than Ruffini endings in other tissues. During regeneration, terminal Schwann cells migrate into regions where they are never found under normal conditions. The development of periodontal Ruffini endings of the rat incisor is closely associated with the eruption of the teeth; the morphology and distribution of the terminal Schwann cells became almost identical to those in adults during postnatal days 15-18 (PN 15-18d) when the first molars appear in the oral cavity, while the axonal elements showed extensive ramification around PN 28d when the functional occlusion commences. When the IAN was injured in neonates, the regeneration of periodontal Ruffini endings was delayed compared with the adults. The migration of terminal Schwann cells is also observed following IAN injury, after which the distribution of terminal Schwann cells became almost identical to that of the adults, i.e., PN 14d. Since the interaction between axon and Schwann cell is important during regeneration and development, further studies are required to elucidate its molecular mechanism during the regeneration as well as the development of the periodontal Ruffini endings.

show abstract

Innervation of the Periodontal Ligament in the Dog with Special Reference to the Morphology of Ruffini Endings.

Cited by 23 publications

References 21 publications

Innervation of the hard palate in the rat studied by anterograde transport of horseradish peroxidase conjugates

Innervation of the hard palate in the rat studied by anterograde transport of horseradish peroxidase conjugates

Histomorphological study of myelinated nerve fibres in the periodontal ligament of human canine

Regeneration of periodontal Ruffini endings in adults and neonates

Contact Info

Product

Resources

About