Innentitelbild: Mechanochemische Freisetzung nichtkovalent gebundener Gäste aus einem mit Polymerketten dekorierten supramolekularen Käfig (Angew. Chem. 24/2021)

Abstract

… im Zentrum eines sternfçrmigen wasserlçslichen Polymers spricht auf eine ultraschallinduzierte Scherkraft in Lçsung an. Wie Robert Gçstl, Bernd M. Schmidt in ihrer Zuschrift auf S. 13738 berichten, verkapselt der oktaedrische Pd-Käfig (blaue Felder), der Polymerketten (rot) an jedem Eckpunkt trägt, pharmazeutisch aktive Frachten in seiner hydrophoben Nanokavität und wird durch Beschallung in wässriger Lçsung aktiviert, was zur vollständigen Freisetzung der Fracht führt.

Mechanochemical Mediated Coexistence of B←N Coordination and Hydrogen Bonding

“…Mechanochemistry provides exciting synthetic opportunities to generate novel functional solid phases and mixtures. The approach allows for the construction of supramolecular architectures predicated to form by directional noncovalent forces such as hydrogen bonding (e.g., cocrystals) and coordination (e.g., B‐nitrogen) [1–5] . The use of mechanochemical force to drive chemical reactivity can promise not only more green and efficient processes to be developed for chemical syntheses but also access to alternative reactivity and mechanistic materials science pathways (e.g., catalytic) [3,6–8] .…”

“…The approach allows for the construction of supramolecular architectures predicated to form by directional noncovalent forces such as hydrogen bonding (e.g., cocrystals) and coordination (e.g., B-nitrogen). [1][2][3][4][5] The use of mechanochemical force to drive chemical reactivity can promise not only more green and efficient processes to be developed for chemical syntheses but also access to alternative reactivity and mechanistic materials science pathways (e.g., catalytic). [3,[6][7][8] A similar argument has been hypothesized for new mechanochemical pathways in prebiotic chemistry from inactivated amino acids in extraterrestrial and terrestrial collisions.…”