Abstract:Toll-like receptors (TLR) play a key role in the innate immune system, providing vertebrates with a critical first line of defense against invading microbial pathogens. With the increasing body of molecular data relating to TLR function, organizing this information is useful to biologists and immunologists. We have used Reactome (www.reactome.org), a manually curated pathway database, to organize TLR data so that it can be viewed like an electronic textbook. TLR signaling cascades were authored by experts, mai… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.