Inlet Patch: Clinical Presentation and Outcome in Children

Georges, Amandine; Coopman, Stéphanie; Rebeuh, Julie; Molitor, Guy; Rebouissoux, Laurent; Dabadie, A.; Kalach, Nicolas; Lachaux, A.; Michaud, Laurent

doi:10.1097/mpg.0b013e3181f2a913

Cited by 23 publications

(15 citation statements)

References 20 publications

(61 reference statements)

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“…When upper endoscopy is performed, the following areas should be carefully examined: upper esophagus, as EA patients are at increased risk of inlet patch;[44] esophagogastric junction; and the anastomosic site. The endoscopist should also be looking for stenosis, diverticulum or fistula, hiatal hernia, peptic changes, or findings suggestive of eosinophilic esophagitis.…”

Section: Gastroesophageal Reflux Diseasementioning

confidence: 99%

How to Care for Patients with EA-TEF: The Known and the Unknown

Mousa

Krishnan

Hassan

et al. 2017

Curr Gastroenterol Rep

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EA patients are at high risk for gastroesophageal reflux and esophageal strictures, and the sequela that result. Extraintestinal manifestations of gastroesophageal reflux disease (GERD) can appear similar to other pathologic diagnoses commonly found in EA patients, such as congenital stricture, eosinophilic esophagitis, esophageal dysmotility, tracheomalacia, recurrent fistula, aspiration, etc. Therefore, it is important to have a standardized way to monitor for these issues. pH impedance allows for detection of nonacid reflux and the height of reflux, which are important in correlating symptoms with reflux episodes. A multidisciplinary approach is beneficial in evaluating and monitoring EA patients in the long term.

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Section: Gastroesophageal Reflux Diseasementioning

confidence: 99%

How to Care for Patients with EA-TEF: The Known and the Unknown

Mousa

Krishnan

Hassan

et al. 2017

Curr Gastroenterol Rep

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“…The largest autopsy series (1000 cases) demonstrated a prevalence of 4.5% in children 4. Several studies estimated CIP prevalence at between 0.03% and 5.9% in children 5. Schridde found microscopic foci present in the inlet area in 70% of autopsies 6.…”

Section: Introductionmentioning

confidence: 99%

“…There is a higher incidence of respiratory symptoms, specifically cough, wheezing and asthma in some,33 and of dysphagia and food impaction in others 5. It should be noted however that these studies were published before the diagnostic criteria for eosinophilic oesophagitis were established, another important change to the Rome IV diagnostic criteria for globus.…”

Section: Introductionmentioning

confidence: 99%

Cervical inlet patch: new insights into diagnosis and endoscopic therapy

Rusu

Ishaq

Wong

et al. 2017

Frontline Gastroenterol

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The cervical inlet patch is an island of heterotopic gastric mucosa, most commonly found in the proximal oesophagus. Its importance as a cause of throat symptoms has been recognised, particularly chronic globus sensation. This has led to a change in the Rome IV criteria for globus management, with emphasis on ruling out the condition. Proton pump inhibitors are often ineffective in resolving symptoms. Endoscopic studies on the use of ablative techniques, most recently radiofrequency ablation (RFA), have shown promise in reversing the CIP to mormal squamous mucosa, with subsequent symtpomatic resolution. The aim of this review is to update on the investigation and management of the CIP.

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“…It is commonly detected as solitary lesion but it can be multiple (1). In a pediatric multicenter retrospective study, 12 of 15 patients had solitary IP (4). Eight of our patients had a solitary patch while one had double and 2 had triple.…”

Section: -10% (4)mentioning

confidence: 61%

Çocuklarda Inlet Patch’in Klinik Önemi

Aydemir

Hizarcioglu

Yilmaz

et al. 2020

Osmangazi̇ Journal of Medicine

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Inlet patch (IP) is an area of heterotopic gastric mucosa located in proximal esophagus. Although the majority of IP are asymptomatic, they may be associated with digestive and respiratory symptoms. We aimed to assess prevalence, endoscopic and histopathological findings, clinical significance and outcome of inlet patch in children.The patients with histopathologically proven IP and aged between 0-18 years old were enrolled. Demographic data, clinical symptoms, endoscopic and histopathological findings, treatment modality, and outcomes were collected from medical records. Retrospective review of 2674 esophagogastroduodenoscopy records revealed 11 (0.41%) children. Eight of our patients had a solitary patch whereas others had two (n=1) or three (n=2). Histopathological evaluation revealed that 9 patients had fundic and 2 patients had antral type gastric mucosa. One patient with hematemesis and other with dysphagia had hyperemic patchy areas of which were colonized by H. pylori. Inlet patch was the only pathological endoscopic finding in 4 patients with a single symptom each: heartburn, dysphagia, hematemesis and hoarseness. Symptoms were completely resolved with PPI treatment in 8 children. Helicobacter pylori eradication was achieved in all infected patients. No respiratory symptom was recorded except hoarseness in one patient. No complications like perforation, stenosis or dysplasia that might be related to IP were recorded at follow-up. We suggest that an IP may accompany or may be responsible for digestive symptoms in children and PPI treatment is effective. Endoscopist should be aware of this condition, especially if the patient has dyspeptic symptoms and normal endoscopic findings.

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Inlet Patch: Clinical Presentation and Outcome in Children

Abstract: IP is an uncommon but almost certainly underrecognized lesion in children, and may be the cause of digestive and respiratory symptoms in some children.

Cited by 23 publications

References 20 publications

How to Care for Patients with EA-TEF: The Known and the Unknown

How to Care for Patients with EA-TEF: The Known and the Unknown

Cervical inlet patch: new insights into diagnosis and endoscopic therapy

Çocuklarda Inlet Patch’in Klinik Önemi

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