Injection Lipolysis for Body Contouring

Duncan, Diane

doi:10.1007/978-3-642-02639-3_6

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…Initially, it was assumed that the apoptosis mechanism would be responsible for the lipolysis process after the application of the substances; however, there is little scientific evidence that this mechanism has an important clinical effect in the process. 5,13,19 In this study, the combination of the substances used promoted the reduction of the fat layer by activating lipolysis. The product used is composed of caffeine, ADIPO-TRAP™ (active substance derived from Sundew or Drosera Ramentacea), ACTIGYM™ (considered a marine active-Plankton extract), and LIPOXYN™ (tripeptide 41), which act in different ways to promote measurement reduction.…”

Section: Discussionmentioning

confidence: 86%

“…It is noteworthy that between applications there may also be swelling in the area, especially during the first 24 to 48 hours after injection, although these reactions are considered expected after therapy. 19 For Vega-López et al, 20 intradermotherapy interventions should be performed analyzing the clinical context of patients, their particular characteristics or hypersensitivity, always taking into account the risk/benefit, to prevent the occurrence of unwanted reactions.…”

Section: Discussionmentioning

confidence: 99%

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Comparative Study of Intradermotherapy With Pressurized Injection System and Needles

et al. 2021

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Intradermotherapy allows for treatment of different aesthetic conditions. Currently, it can be applied in its conventional form using needles or using the pressurized technique. The sample consisted of 35 women with adiposity located in the abdominal region. The volunteers were randomly assigned to 3 subgroups: G1 (n = 12) who were subject to the pressurized technique and the conventional technique with needles using only saline substance, with 6 volunteers in each application mode; G2 (n = 9), who received pressurized application using Concept Ti Liporedutor (lipolytic substance); and G3 (n = 14), who were treated with the needle injection technique, with the same substance used in G2. All groups received 4 treatment sessions with 2-week intervals between them. The analysis of the fat layer conducted 90 days after the initial application demonstrated a significant reduction in measurements in the treated groups, and also when compared with the control group, both for ultrasound, perimetry, and plicometry (only right side) data. Despite the effectiveness of the 2 application techniques, the pressurized method showed superior results. Hyperemia and skin marks were among the adverse reactions reported by the groups, but they showed quick resolution. It is noteworthy that most of the volunteers in the treated groups evaluated the results positively and were satisfied with the treatment. The intradermotherapy protocol with lipolytic substance significantly reduced the fat layer, with more evident results when using the pressurized application method.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Comparative Study of Intradermotherapy With Pressurized Injection System and Needles

et al. 2021

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“…Deoxycholate is a bile acid that works as a detergent of lipids and cell membranes [8,10,11]. Recent studies have shown that it is deoxycholate alone [12] that results in the reduction of fat cells through toxic necrolysis, due to a direct effect on the fat cells and surrounding tissue [13]. In this unabated manner, deoxycholate causes profound cell wall disruption and cytolytic effects of not only adipose cells but also fibroblast-like preadipocytes, vascular and skeletal muscle cells, and renal epithelial cells.…”

Section: Discussionmentioning

confidence: 99%

Multisystem Organ Failure Following LipoDissolve Injections

B??R??

Libby²,

Ruha³

et al. 2013

J Clin Toxicol

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LipoDissolve, also known as injection lipolysis, is a procedure marketed as a means to rid the body of unwanted pockets of fat. Despite warnings by the Food and Drug Administration that the products used in this procedure have not been shown to be safe or effective and are not approved for this use, LipoDissolve continues to be used by beauty spas across the United States. The authors report a case of a 63-year-old woman who developed acute liver injury, acute renal failure necessitating hemodialysis, and pancreatitis soon after undergoing her first LipoDissolve therapy at a home spa.

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Laser-Assisted Lipolysis Versus Surgical Fat Removal: A Review of Efficacy, Safety, and Patient Satisfaction

Lee,

Chan,

Lee

et al. 2024

Cosmetics

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(1) Background: The demand for body-contouring procedures has surged, with lipolysis emerging as a common technique for excess fat removal. Laser-assisted lipolysis (LAL) has gained attention as a potential alternative to surgical fat removal (SFR), offering perceived advantages in safety and efficacy. However, the comparative benefits of LAL and SFR remain uncertain. (2) Objective: To conduct a review of the existing literature comparing the efficacy, safety, and patient satisfaction of LAL and SFR. (3) Methods: A comprehensive search of major electronic databases was conducted to identify studies comparing LAL and SFR for body-contouring procedures. Studies were included if they were published in English, involved human subjects, and reported outcomes for LAL and SFR. All studies were classified according to the Oxford Center for Evidence-Based Medicine evidence hierarchy (4) Results: LAL may not be a safer and more effective option than SFR. However, the evidence for these differences was limited by the quality of the studies and the heterogeneity of the results. (5) Conclusions: This review suggests that LAL may not be a safer and more effective option than SFR for body-contouring procedures because LAL is associated with higher risks of complications such as burns and scarring, whereas SFR offers a more established safety profile and consistent efficacy.

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Injection Lipolysis for Body Contouring

Cited by 3 publications

References 8 publications

Comparative Study of Intradermotherapy With Pressurized Injection System and Needles

Comparative Study of Intradermotherapy With Pressurized Injection System and Needles

Multisystem Organ Failure Following LipoDissolve Injections

Laser-Assisted Lipolysis Versus Surgical Fat Removal: A Review of Efficacy, Safety, and Patient Satisfaction

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