2023
DOI: 10.1021/acsbiomaterials.3c00822
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Injectable Self-Harden Antibiofilm Bioceramic Cement for Minimally Invasive Surgery

Xiaofang Li,
Zexu Ma,
Congping Wu
et al.

Abstract: There is an urgent demand for antibacterial bone grafts in clinics. Worryingly, the misuse and overuse of antibiotics accelerate the emergence of drug-resistant bacteria. Therefore, this study prepared a novel injectable bioceramic cement without antibiotics (FS-BCS), which showed good antibacterial properties by loading iron and strontium onto a matrix composed of brushite and calcium sulfate. The setting time, injectability, microstructure, antibacterial properties, anti-biofilm properties, and cytocompatibi… Show more

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