2020
DOI: 10.1016/j.carbpol.2020.116575
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Injectable bone substitute based on chitosan with polyethylene glycol polymeric solution and biphasic calcium phosphate microspheres

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Cited by 25 publications
(18 citation statements)
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“…84 To create a more cohesive and porous material, chitosan and polyethylene glycol were combined with these ceramic microspheres to create a better injectable and mechanically stable implant. 84 For example, while chitosan alone is anti-inammatory it has low mechanical stiffness and calcium-phosphate ceramics are brittle with low porosity, its combination with chitosan can yield a composite with benets of both to create a more stable material able to regenerate greater host bone with minor inammation. Many novel materials developed currently, include hydroxyapatite coatings 47,60 and metal or ceramics particles 45,46,[53][54][55]75 incorporated into polymeric base materials to increase mechanical stability and osteogenesis.…”
Section: Compositesmentioning
confidence: 99%
“…84 To create a more cohesive and porous material, chitosan and polyethylene glycol were combined with these ceramic microspheres to create a better injectable and mechanically stable implant. 84 For example, while chitosan alone is anti-inammatory it has low mechanical stiffness and calcium-phosphate ceramics are brittle with low porosity, its combination with chitosan can yield a composite with benets of both to create a more stable material able to regenerate greater host bone with minor inammation. Many novel materials developed currently, include hydroxyapatite coatings 47,60 and metal or ceramics particles 45,46,[53][54][55]75 incorporated into polymeric base materials to increase mechanical stability and osteogenesis.…”
Section: Compositesmentioning
confidence: 99%
“…Structure imperfections due to the presence of vacancies, impurities of implementation and substitution, and determined by them distortions in the crystal lattice became energetically advantageous for the formation of HAP in the hexagonal syngony. Therefore, the presence of microimpurities and other defects in the structure of biological apatite Atoms of impurity can be located randomly in the structure of hydroxyapatite [61]. To describe the structure of HAP, it is convenient to formulate the ideal stoichiometric formula of Ca 10 (PO 4 ) 6 (OH) 2 , taking into account the different positions occupied by calcium atoms in the lattice of HAP as Ca 10 (PO 4 ) 6 (OH) 2 , and also calculating the Ca/P ratio, which for our samples was 1.5.…”
Section: Obtaining Of Biologically Soluble Membranes Based On Polymermentioning
confidence: 99%
“…Já, quando a variável valor unitário passa pela transformação logarítmica (ln VU), há uma correção, resultando em uma curva de assimetria levemente negativa e platicúrtica, com a função de distribuição mais achatada. Fonte: Autores (2020).…”
Section: Análise Exploratória Dos Dadosunclassified
“…Em geral, essa valorização dos dois bairros em estudo foi melhor capturada pela PVG obtida pela krigagem da modelagem GWR. Krigagem: RMSE para os valores preditos pela amostra de trabalho.Fonte: Autores(2020).Observa-se que a modelagem GWR apresentou RMSE menor, indicando que esse modelo foi capaz de fazer predições mais próximas do esperado. Calculou-se o RMSE dos valores preditos pelas krigagens para a amostra de validação.…”
unclassified