Initiation of human parturition

Schwarz, Barry E.; Schultz, F. Michael; MacDonald, Paul C.; Johnston, John M.

doi:10.1016/0002-9378(76)90813-9

Cited by 36 publications

(1 citation statement)

References 3 publications

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“…Spontaneous preterm deliveries that occur before 34 weeks of gestation, have been strongly associated with intrauterine infection. 25 Bacterial vaginosis (40.74%) was the most common organism isolated from the high vaginal swab in our study. Data presented in various work have demonstrated strong associations between prevalent infection of BV and preterm birth.…”

Section: Resultsmentioning

confidence: 54%

Evaluation of Genitourinary Infection in Preterm Labour: A Descriptive Cross-Sectional Study

Shrestha,

Mushtaq,

Shah

et al. 2023

Medphoenix

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Introduction: Preterm labour is defined as the occurrence of regular uterine contractions (≥ 4 in 20 minutes or ≥ 8 in 1 hour) and cervical changes (effacement ≥ 80% and dilatation ≥ 1cm) in women with intact fetal membrane and gestational age less than 37 weeks. Genitourinary infection is the most important cause of preterm labour. The aim of this study was to determine the role of Genitourinary infection in causation of preterm labour. Methods: This is a descriptive cross sectional study done at National Medical College Teaching Hospital from 10 November 2021 to 9 November 2022 after obtaining IRC (F-NMC/549/078-79). Total of 90 patients in preterm labour fulfilling the inclusion criteria were enrolled in this study after taking informed consent. Clinical examination was done, vaginal swab, endocervical swab and urine samples were sent to microbiological department for examination. Preformed proforma were used to record the demographic, clinical finding and result of investigation. The data was analyzed statistically using SPSS 22 and mean age, frequency and prevalence of genitourinary infection were calculated. Results: In this study, 90 patients of preterm labour were enrolled. The mean age group of patients was 23.61 ± 4.25 years. Genital infection compromised of 41%, high vaginal swab showed 30% prevalence and endocervical swab showed 20% prevalence. The most common organism identified in genital infection was Gardenella vaginalis 55.55%. The prevalence of Urinary tract infection was 40% where E.coli was the most common organism 66.66%. Conclusions: Genitourinary tract infection plays an important role in causation of preterm labour and can easily be diagnosed with routine urine examination, urine culture and vagino-cervical swab. The prevalence of genital infections and urinary tract infection was 41% and 40% respectively. Gardnerella vaginalis was the most common pathogen identified in genital tract whereas E.coli was leading cause of UTI in Preterm labour patients.

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Section: Resultsmentioning

confidence: 54%

Evaluation of Genitourinary Infection in Preterm Labour: A Descriptive Cross-Sectional Study

Shrestha,

Mushtaq,

Shah

et al. 2023

Medphoenix

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Developmental changes in the fine structure of the chorion laeve (Smooth chorion) of the rhesus monkey placenta

King

1981

Anat. Rec.

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Developmental changes in the fine structure of the chorion laeve (smooth chorion) of the rhesus monkey were studied at two time periods during gestation: 1) Early (19-60 days of gestation), before the chorionic epithelium fuses with the parietal decidua, and 2) near term, when the fused chorioamnion has also fused with the parietal decidua. Early in gestation the chorionic epithelium consisted of columnar and cuboidal cells one or two layers thick. The apical border of the cells had microvilli and coated pits, and adjacent cells were joined by tight junctions and desmosomes. The chorionic epithelial cells during this early period contained numerous large vesicles and vacuoles of varying electron-density. The apical cytoplasm contained various small coated vesicles and tubules. Taken together these observations were interpreted as indicating a possible role for these cells in endocytosis or phagocytosis of substances from the uterine lumen; i.e., a potential role in histiotrophic nutrition during this early period. Late in gestation the trophoblastic cells were more irregular in shape. The cells contained abundant granular endoplasmic reticulum (ER) and mitochondria, and a well-developed Golgi complex, suggesting the cells were actively synthetic late in gestation. The numerous cytoplasmic vacuoles characteristic of the trophoblastic cells of early gestation were absent near term. Glycogen deposits and lipid droplets were moderately well-developed near term. Most of the cells were joined by desmosomes but wide intercellular spaces, unobstructed by any cell junctions, were frequently observed. This observation provides at least one explanation for the increase in permeability of the chorion laeve later in gestation. Cells of the parietal decidua associated with the chorion laeve were also examined. These cells generally had a well-developed granular ER and Golgi apparatus, and numerous mitochondria. Limited numbers of membrane-bounded secretory bodies, similar to those in human decidual cells, were also present.

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Essential Fatty Acids and Prostaglandins in Pregnancy

Ogburn¹

1998

Principles of Perinatal—Neonatal Metabolism

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Initiation of human parturition

Cited by 36 publications

References 3 publications

Evaluation of Genitourinary Infection in Preterm Labour: A Descriptive Cross-Sectional Study

Evaluation of Genitourinary Infection in Preterm Labour: A Descriptive Cross-Sectional Study

Developmental changes in the fine structure of the chorion laeve (Smooth chorion) of the rhesus monkey placenta

Essential Fatty Acids and Prostaglandins in Pregnancy

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