Initial presenting symptoms andseverity of SARS-CoV-2 Wild type, theDelta variant and the Omicron variant infected cases in early fourth wave ofepidemics in Myanmar

Pyar, Khin Phyu

doi:10.52845/jmrhs/2022-5-1-8

Cited by 1 publication

(2 citation statements)

References 5 publications

(5 reference statements)

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“…Such a mutation profile not only increases infectivity but characterizes clinical symptoms of the Omicron variant. It is becoming evident that patients infected with the Omicron variant complain of ageusia and dysgeusia with a relatively low frequency compared with other SARS-CoV-2 strains and variants [ 87 , 88 ]. Xerostomia is very unlikely to occur frequently in patients infected with the Omicron variant as only one case was reported in the Omicron infection [ 89 ].…”

Section: Resultsmentioning

confidence: 99%

“…Comparative studies have suggested that serum zinc concentrations are significantly decreased in COVID-19 patients and that hypozincemia persists after recovery from COVID-19. Yasui et al [86] studied Japanese CO-VID-19 patients who had been admitted to ICU and finally discharged from hospital after treatment; these patients had serum zinc concentrations below or near the [87,88]. Xerostomia is very unlikely to occur frequently in patients infected with the Omicron variant as only one case was reported in the Omicron infection [89].…”

Section: Trpv1 Interacting With Sars-cov-2mentioning

confidence: 99%

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COVID-19 Oral Sequelae: Persistent Gustatory and Saliva Secretory Dysfunctions after Recovery from COVID-19

Tsuchiya¹

2023

Med Princ Pract

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Diverse manifestations have been recognized to last for a long time in patients infected with SARS-CoV-2. However, understanding of oral sequelae after recovery from COVID-19 is relatively poor compared to that of oral symptoms in the acute phase of COVID-19 and other COVID-19 sequelae. The aim of the present study was to characterize persistent gustatory and saliva secretory dysfunctions and to speculate on their pathogenic mechanisms. Articles were retrieved by searching scientific databases with a cutoff date of September 30, 2022. The literature search indicated that ageusia/dysgeusia and xerostomia/dry mouth are reported by 1–45% of COVID-19 survivors at follow-ups of 21–365 days and by 2–40% of COVID-19 survivors at follow-ups of 28–230 days, respectively. The prevalence of gustatory sequelae partly depends on difference in ethnicity, gender, age, and disease severity of subjects. Co-occurring gustatory and saliva secretory sequelae are pathogenically related to either or both of the following: expression of SARS-CoV-2 cellular entry-relevant receptors in taste buds and salivary glands, and SARS-CoV-2 infection-induced deficiency in zinc that is essential for normality of taste perception and saliva secretion. Given the long-term oral sequelae, hospital discharge is not the end of the disease; therefore, careful attention should be continuously paid to oral conditions of post-COVID-19 patients.

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Section: Resultsmentioning

confidence: 99%