Initial interfacial healing events around calcium phosphate (Ca‐P) coated oral implants

Abstract

The bone response to different calcium phosphate (Ca‐P) coated and non‐coated titanium implants was evaluated in a goat animal model. Two types of Ca‐P coatings have been investigated: an experimental plasma‐spray bi‐layered Ca‐P coating (FA‐HA) and an amorphous RF magnetron sputter coating (Ca‐P‐a). Fifty‐four conical screw shaped implants were inserted in the lateral and medial femoral condyles of 18 Saanen goats. After implantation periods of 3, 12 and 24 days, the bone‐implant interface was evaluated histologically and histomorphometrically. Light microscopical evaluation revealed that bone formation on the Ca‐P coated implants proceeded faster. At 24 days higher percentages of bone contact were measured for both Ca‐P coated implants than for non‐coated implants. However, this difference was only significant for the FA‐HA coated implants. On basis of these findings. we concluded that Ca‐P coatings show improved bone response due to an initial difference in bone cell response.

Application of fluoridated hydroxyapatite thin film coatings using KrF pulsed laser deposition

“…Many arguments have been made both in opposition to and in favor of the use of HA coatings 34) . This debate has been fueled by the failures of clinical implants, supposedly as a result of poor coating-substrate adherence and problems with the crystallinity of the coating [9][10][11] .…”

Platelet interactions with calcium-phosphate-coated surfaces

“…Many studies have shown that calcium-phosphate (CaP)-coated endosseous implants exhibit more periimplant bone formation and more bone contact at early healing times than uncoated implants [1][2][3][4][5]. Such bone formation on an implant depends upon the presence of a secretorily active osteoblast population at the implant surface.…”

Calcium Orthophosphates (CaPo ) and Dentistry

“…Since CaPO 4 do not cause inflammation [307], they could be used as a hard plug deep inside teeth [309]. Finally yet importantly, CaPO 4 crowns were manufactured [518].…”