2003
DOI: 10.1081/jcmr-120025232
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Initial Experiences with In Vivo Right Coronary Artery Human MR Vessel Wall Imaging at 3 Tesla

Abstract: Due to their relatively small size and central location within the thorax, improvement in signal-to-noise (SNR) is of paramount importance for in vivo coronary vessel wall imaging. Thus, with higher field strengths, coronary vessel wall imaging is likely to benefit from the expected "near linear" proportional gain in SNR. In this study, we demonstrate the feasibility of in vivo human high field (3 T) coronary vessel wall imaging using a free-breathing black blood fast gradient echo technique with respiratory n… Show more

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Cited by 56 publications
(33 citation statements)
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“…A previous study using the DIR-GRE sequence which performed coronary vessel wall imaging at 3T found that, after adjustments for longer T1 times and the frequency offset for fat suppression, an SNR gain of 50% could be achieved in cross-sectional images (12). GE spiral imaging is sensitive to off-resonance effects, which is especially pronounced in cardiac imaging where the FOV contains numerous air-tissue interfaces.…”
Section: Discussionmentioning
confidence: 99%
“…A previous study using the DIR-GRE sequence which performed coronary vessel wall imaging at 3T found that, after adjustments for longer T1 times and the frequency offset for fat suppression, an SNR gain of 50% could be achieved in cross-sectional images (12). GE spiral imaging is sensitive to off-resonance effects, which is especially pronounced in cardiac imaging where the FOV contains numerous air-tissue interfaces.…”
Section: Discussionmentioning
confidence: 99%
“…During the developmental phase of our protocol, we initially focused on the use of dual-inversion FSE imaging as well. However, based on our prior experience with black-blood imaging of the coronary vessel wall at 1.5T and 3T (30,31), we decided to simultaneously work on the development of a dual-inversion SPGRE technique. We found that both the visual sharpness and contrast of the carotid vessel wall were superior on the SPGRE images as compared to those obtained with the more conventional FSE approach.…”
Section: Discussionmentioning
confidence: 99%
“…In earlier studies conducted in both healthy adults and in patients, two-dimensional DIR fast spin echo imaging (19,20) or three-dimensional DIR spiral imaging (22) was used at 1.5 T. At 3 T, the first coronary vessel wall data were acquired using a three-dimensional, free-breathing, segmented, k-space, gradient echo imaging technique (48). Three-dimensional imaging was utilized in this early 3-T study for sufficient SNR.…”
Section: Discussionmentioning
confidence: 99%