Initial Experience with the BioSig PURE EP™ Signal Recording System: An Animal Laboratory Experience

Abstract

ABSTRACT. Current signal recording and processing systems have come a long way since their initial inception and use. There is, however, still ample scope for improvement, not only in the troubleshooting of their limitations, but also in the expansion of the boundaries in the recording of intracardiac signals. Here, we recount our experience with the use of the PURE EPt signal recording system (BioSig Technologies, Inc., Minneapolis, MN, USA) in the animal laboratory.

The circuit for bundle‐branch re‐entrant tachycardia

“…This, however, is not unusual since there may be proximal right bundle‐branch block and the pacing site distal to the site of block such that an antegrade bundle signal is not seen in sinus rhythm and with retrograde conduction system located at this site being activated after a myocardial wavefront from exit in the left ventricle (antegrade left bundle conduction). The local conduction signal may be hidden within the ventricular electrogram 5 …”

“…The local conduction signal may be hidden within the ventricular electrogram. 5 Liu et al, 2 present a pace that highlights the vagaries and extreme difficulty with identifying the entire circuit of bundle-branch reentry. Invasive electrophysiologists, therefore, focus on the proximal conduction system using all available mapping approaches to see how likely the proximal right or left bundle is a part of the circuit and target this site for ablation.…”

Innovations in Clinical Cardiac Electrophysiology: Challenges and Upcoming Solutions in 2018 and Beyond

“…An advanced signal processing system allows for the visualization of the Purkinje signal separate from the local myocardial activation. 111 This is achieved by using a highpass filter with additional processing. Local myocardial depolarization can result in large local depolarization signals, and signal processing beyond a linear high-pass filter is required for Purkinje potential display (Figure 3).…”