Abstract:This initial experience showed dexmedetomidine, with or without the addition of propofol, may be a suitable alternative for sedation in spontaneously breathing patients undergoing cardiac catheterization.
“…Dexmedetomidine has been found to be useful in sedation during mechanical ventilation, prevention of emergence delirium, after general anaesthesia and procedural sedation during noninvasive radiological procedures [49]. Munro et al, [50] reported dexmedetomidine as the primary agent for sedation during cardiac catheterization in infants and children. Kristin et al, [51] suggested that invasive procedures can successfully be performed in spontaneously breathing infants and toddlers with congenital heart disease using dexmedetomidine 1-3 mcg/ kg alone or in addition to low dose ketamine.…”
“…Dexmedetomidine has been found to be useful in sedation during mechanical ventilation, prevention of emergence delirium, after general anaesthesia and procedural sedation during noninvasive radiological procedures [49]. Munro et al, [50] reported dexmedetomidine as the primary agent for sedation during cardiac catheterization in infants and children. Kristin et al, [51] suggested that invasive procedures can successfully be performed in spontaneously breathing infants and toddlers with congenital heart disease using dexmedetomidine 1-3 mcg/ kg alone or in addition to low dose ketamine.…”
“…Limited data on adult population undergoing dental procedural sedation with dexmedetomidine has shown it to efficacious and safe with sufficient analgesia, but limited amnesia and prolonged recovery time [47][48][49][50] . Although generally effective for sedation for noninvasive and short procedure, dexmedetomidine as sole agent has not been uniformly successful for invasive procedures [51][52][53][54][55] . It is slowly losing the popularity as sole agent for procedural sedation due to its slow onset, delayed recovery, minimal analgesia and limited amnesia.…”
“…It has been successfully used for diagnostic radiologic procedures, like MRI and CT scans, and for invasive procedures, like placement of central venous lines in infants, bronchoscopy and laryngoscopy, cardiac catheterization and others 59,60 . Dexmedetomidine has been also used to provide sedation in the postanesthesia care unit following sevoflurane anesthesia to decrease the incidence of agitation in the pediatric population, and to allow intubation in a sedated pediatric patient.…”
Summary: Afonso J, Reis F -Dexmedetomidine: Current Role in Anesthesia and Intensive Care.
Background and objectives:To update and review the application of dexmedetomidine in anesthesia and intensive care. This study is a comprehensive review of clinical uses, pharmacology, pharmacokinetics, mechanism of action and adverse effects of dexmedetomidine.
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