Initial clinical results with a fusion prototype for mammography and three-dimensional ultrasound with a standard mammography system and a standard ultrasound probe

Abstract

Background: Combinations of different imaging techniques in fusion devices appear to be associated with improvements in diagnostic assessment. Purpose: The aim of this study was to test the feasibility of using an automated standard three-dimensional (3D) ultrasound (US) device fused with standard mammography for the first time in breast cancer patients. Material and Methods: Digital mammograms and 3D automated US images were obtained in 23 patients with highly suspicious breast lesions. A recently developed fusion machine consisting of an ABVS 3D US transducer from an Acuson S2000 machine and a conventional Mammomat Inspiration device (both Siemens Healthcare GmbH, Erlangen, Germany) were used for the purpose. The feasibility of the examinations, imaging coverage, and patients' experience of the procedure were examined. Results: In 15 out of 19 patients, the region of interest (ROI) with the tumor marked in the mammogram was visible on US. The examination was experienced positively by the patients, with no unexpected pain or injury. The examination was time-saving and well tolerated. Conclusion: In conclusion, we have shown initial clinical feasibility of an US/radiography fusion prototype with good localization and evaluation of the ROIs. The combined examination was well tolerated. The simultaneous evaluation with mammography and US imaging may be able to improve detection and reduce examiner-related variability.

Risk, Prediction and Prevention of Hereditary Breast Cancer – Large-Scale Genomic Studies in Times of Big and Smart Data

“…3 ). With technical advances like the fusion of several imaging methods 92 , 93 , automated assessment of mammographic density 94 and diagnostic accuracy of mammography 95 as well as the integration of big data and machine learning into patient and tumor assessments 96 , 97 such individualized screening strategies seem to be feasible and several studies are already ongoing 98 , 99 , 100 , 101 , 102 .…”

Evaluation of Physical Properties and Image of Polyvinyl Chloride as Breast Tissue Equivalence for Dual-Modality (Mammography and Ultrasound)

“…Moro et al, 2020 [4] combined Magnetic Resonance Imaging (MRI) and ultrasonography (US) images to improve cervical cancer assessment. Emons et al 2018 [5] also developed a prototype of a combination between mammography and US images to improve breast cancer detection. Berg et al 2004 [6] compared the evaluation of breast images from clinical examination using US, mammography, MRI, as well as multimodal and single modality.…”