Initial changes of non-traumatic osteonecrosis of femoral head in fat suppression images: bone marrow edema was not found before the appearance of band patterns

Fujioka, Mikihiro; Kubo, Toshikazu; Nakamura, Fuminori; Shibatani, Masahiko; Ueshima, Keiichiro; Hamaguchi, Hiroyuki; Inoue, Shigehiro; Sugano, Nobuhiko; Sakai, Takashi; Torii, Yukio; Hasegawa, Yukiharu; Hirasawa, Yasusuke

doi:10.1016/s0730-725x(01)00424-6

Cited by 57 publications

(33 citation statements)

References 23 publications

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“…MRI was performed as previously described (Kubo et al 1997, Fujioka et al 2001) using a 0.5-tesla superconducting magnet (in the period 1988–1990) or a 1.5-tesla superconducting magnet (in the period 1990–2008). T1-weighted images, T2-weighted images, and fat suppression images (short TI inversion recovery, STIR) on the coronal plane were obtained.…”

Section: Methodsmentioning

confidence: 99%

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Corticosteroid administration within 2 weeks after renal transplantation affects the incidence of femoral head osteonecrosis

et al. 2014

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Background and purposeIt has been suggested that avascular osteonecrosis (AVN) of the femoral head occurs early after systemic steroid administration. The purpose of this study was to investigate the risks regarding development of AVN at a very early stage after renal transplantation.MethodsThe presence or absence of AVN was determined by MRI at 4 weeks, at 6–12 weeks, at 24 weeks, and at 12 months after renal transplantation in 286 patients (183 males) with a mean age of 39 (16–65) years. The relationship between AVN and age, sex, absence or presence of acute rejection (AR), type of transplanted kidney (living or cadaveric), type of immune suppressor, and total dose of orally administered steroids given in the 2-week period after transplantation was investigated.ResultsThere were no statistically significant correlations between the development of AVN and age, sex, absence or presence of AR, type of transplanted kidney, or type of immune suppressor. A significant dose-response relationship was found between development of AVN and the total dose of steroid administered in the first 2 weeks after surgery.InterpretationWe found a relationship between AVN development and steroid dose in the early postoperative period, and we also showed a dose-response relationship.

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Section: Methodsmentioning

confidence: 99%

“…In patients who have undergone renal transplantation, T1-weighted MRI shows a band pattern in the femoral head at around 6–12 weeks postoperatively (Kubo et al 1997, Fujioka et al 2001). This indicates that AVN occurs very early after renal transplantation.…”

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Corticosteroid administration within 2 weeks after renal transplantation affects the incidence of femoral head osteonecrosis

et al. 2014

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“…AVN is a major postoperative complication that develops within 12 weeks (Kubo et al 1997, Fujioka et al 2001 with a reported incidence of 3-40% (Harrington et al 1971, Gustafsson et al 1976, Ibels et al 1978, Anderson and Nielsen 1981, Bradford et al 1983, Julian et al 1992, Tang et al 2000. It has been shown that the total dose in a 1-year period or average daily dose of steroids is related to the risk of development of AVN (Harrington et al 1971, Pierides et al 1975, Chatterjee et al 1976, Patton and Plaff 1988, Tang et al 2000.…”

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confidence: 99%

Degree of corticosteroid treatment within the first 2 months of renal transplantation has a strong influence on the incidence of osteonecrosis of the femoral head

Shibatani¹,

Fujioka²,

Arai³

et al. 2008

Acta Orthopaedica

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Degree of corticosteroid treatment within the first 2 months of renal transplantation has a strong influence on the incidence of osteonecrosis of the femoral head, Acta Orthopaedica, 79:5, 631-636, DOI: 10.1080 Background and purpose It has been suggested that avascular osteonecrosis (AVN) of the femoral head develops early after renal transplantation. We evaluated the relationship between risk of AVN and dose of steroids administered in different time periods.Methods Development of AVN was determined using MRI at 3-6 weeks, 9-12 weeks, 24 weeks, and 12 months after transplantation in 150 patients (96 males). We investigated possible associations between acute rejection reactions, the dose of cyclosporine, tacrolimus use, total steroid dose by the second, fourth, sixth, or eighth weeks after transplantation, and incidence of AVN.Results There was no statistically significant difference between incidence of AVN and presence or absence of an acute rejection reaction. We found a statistically significant association between AVN incidence and the total dose of steroids administered during the first 2 months after transplantation, and there was a doseresponse relationship. No other statistically significant associations were found.Interpretation Our findings confirm that the total dose of steroids given within the first 2 months after renal transplantation has a great influence on the incidence of AVN.

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“…It has been shown that patients with ON of the femoral head do not have findings of BME typical for TOH in the early stages of the disease [37]. In a study presenting early findings in ON, BME was never found before the appearance of band patterns, suggesting that the latter are actually the initial ON changes which are not expected in TOH [38]. A similar study showed that a band pattern is the initial MR imaging finding of early ON without any prior diffuse BME depicted [39].…”

Section: Differential Diagnosis Of On and Tohmentioning

confidence: 96%

Acute bone marrow edema of the hip: role of MR imaging

Karantanas

2007

Eur Radiol

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Acute bone marrow edema of the hip is a diagnostic challenge for both radiologists and clinicians. Marrow edema is often seen in patients with hip pain and restriction of motion. In patients with acute non-traumatic hip pain, whose radiographs are negative or inconclusive, MR imaging is the imaging study of choice. MR imaging is the most sensitive and specific imaging technique for detecting transient osteoporosis and osteonecrosis, as well as for detecting and staging fractures and microfractures. MR imaging is able to show marrow involvement in various inflammatory disorders and to diagnose reactive marrow edema from femoroacetabular impingment and greater trochanteric pain syndrome. In patients with septic arthritis, it may also depict associated marrow edema and suggest its reactive or infectious origin. For the neoplastic disorders, although plain radiographs should be the initial examination, MR imaging may follow for assessing extension to the surrounding soft tissues and/or associated pathologic fracture, facilitating thus the treatment planning. Computed tomography is more accurate compared with MR imaging in diagnosing intra-articular osteoid osteomas.

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Initial changes of non-traumatic osteonecrosis of femoral head in fat suppression images: bone marrow edema was not found before the appearance of band patterns

Cited by 57 publications

References 23 publications

Corticosteroid administration within 2 weeks after renal transplantation affects the incidence of femoral head osteonecrosis

Corticosteroid administration within 2 weeks after renal transplantation affects the incidence of femoral head osteonecrosis

Degree of corticosteroid treatment within the first 2 months of renal transplantation has a strong influence on the incidence of osteonecrosis of the femoral head

Acute bone marrow edema of the hip: role of MR imaging

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